Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.040 GeneticVariation BEFREE Here we report a PV patient heterozygous for the somatic JAK2(N542-E543del) mutation and a previously unreported germline mutation within the SH2 domain of SOCS3 (F136L). 19735488

2009
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.040 GeneticVariation BEFREE SOCS3 transcript levels were highest in patients with polycythemia vera and other JAK2 V617F positive myeloproliferative disorders, consistent with SOCS3 being a target gene of JAK2/STAT5 signaling. 18815196

2008
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.040 GeneticVariation BEFREE The evolving evidence that JAK2 V617F is not specific for polycythemia vera pathogenesis and the development of disease phenotype is presented as well as alternative candidates for pathogenic mutations such as the protein tyrosine phosphatases and SOCS-3. 16781479

2006