Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1896
Gene Symbol: EDA
EDA
CUI: C0080233
Disease: Tooth Loss
Tooth Loss
0.030 GeneticVariation BEFREE Genetic variations in genes known to be associated with EDs that affect only one derivative of the ectoderm (attenuated phenotype) will be grouped as non-syndromic traits of the causative gene (e.g., non-syndromic hypodontia or missing teeth associated with pathogenic variants of EDA "ectodysplasin"). 30703280

2019

Entrez Id: 1896
Gene Symbol: EDA
EDA
CUI: C0080233
Disease: Tooth Loss
Tooth Loss
0.030 Biomarker BEFREE PAX9, MSX1, AXIN2, WNT10A and EDA have been experimentally established for congenitally missing teeth like hypodontia and oligodontia. 25203534

2014

Entrez Id: 1896
Gene Symbol: EDA
EDA
CUI: C0080233
Disease: Tooth Loss
Tooth Loss
0.030 Biomarker BEFREE Significant differences in the number of some primary missing teeth (incisor and canine) related to EDA-EDAR genes defects were detected for the first time between XLHED and autosomal recessive HED, suggesting differential local effects of EDA-EDAR genes during odontogenesis. 20236127

2010