Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker BEFREE We have previously reported that, in a phase I pilot study (ClinicalTrials.gov NCT00095862), a subject with stage IV breast cancer experienced substantial regression of breast, lung, and brain lesions following inoculation with clinical formulations of SV-BR-1-GM, a GM-CSF-secreting breast tumor cell line. 29867922

2018

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker BEFREE Thus, we explored the potential immune-modulating effects of sorafenib in a murine HER-2-(neu) overexpressing breast tumor model alone and in combination with a HER-2 targeted granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting vaccine (3T3neuGM). 28282575

2017

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker BEFREE Immunization with two recombinant Bacillus Calmette-Guérin vaccines that combine the expression of multiple tandem repeats of mucin-1 and colony stimulating-factor suppress breast tumor growth in mice. 20127358

2010

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker BEFREE First, immunotherapy with an allogeneic, HER2-positive, GM-CSF-secreting breast tumor vaccine alone or with CY and DOX is safe and induces HER2-specific immunity in patients with metastatic breast cancer. 19805669

2009

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker BEFREE Hyaluronan-mediated CD44 interaction with RhoGEF and Rho kinase promotes Grb2-associated binder-1 phosphorylation and phosphatidylinositol 3-kinase signaling leading to cytokine (macrophage-colony stimulating factor) production and breast tumor progression. 12748184

2003