Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker PSYGENET Reduced expression of α-synuclein in alcoholic brain: influence of SNCA-Rep1 genotype. 22974310

2014
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker PSYGENET Preclinical studies implicate the gene encoding the alpha synuclein protein (SNCA) in the pathophysiology of alcohol dependence and dopamine neuron function. 23384371

2013
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker CTD_human Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers. 18055133

2008
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker PSYGENET These results suggest that variation in SNCA contributes to alcohol craving, a common, although not uniform, feature of alcohol dependence. 17374032

2007
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker PSYGENET We observed a significant increase of the alpha synuclein promoter DNA methylation in patients with alcoholism which was significantly associated with their elevated homocysteine levels. 15671870

2005
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.580 Biomarker PSYGENET Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence. 15731118

2005