Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker PSYGENET In some individuals, the ADRBK2 gene harbors the A-haplotype, a collection of single nucleotide polymorphisms (SNPs) previously associated with an increased risk for bipolar disorder. 19766236

2010

Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker PSYGENET The genes most consistently associated with BD in the genetic studies we reviewed were GSK3beta , GRK3, 5-HTTLPR, GRIN3, COMT, and GLUR3. 20226637

2010

Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker PSYGENET Decreased expression of G-protein subunits and of GRK3 may alter neurotransmission, leading to disturbed cognition and behaviour in BD. 19400979

2009

Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker PSYGENET Promoter variant in the GRK3 gene associated with bipolar disorder alters gene expression. 18359007

2008

Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker PSYGENET Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation. 18075471

2007

Entrez Id: 157
Gene Symbol: GRK3
GRK3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.560 Biomarker CTD_human Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder. 12808434

2003