Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.600 Biomarker PSYGENET Suicidal behavior in the context of disrupted rhythmicity in bipolar disorder--data from an association study of suicide attempts with clock genes. 25724486

2015

Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.600 Biomarker PSYGENET Clock genes have been implicated in several disorders, such as schizophrenia, bipolar disorder, autism spectrum disorders, and drug dependence. 24865659

2014

Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.600 Biomarker PSYGENET We genotyped 42 polymorphisms from circadian clock genes: PER3, ARNTL, CLOCK and TIMELSSS from 511 patients BD (n = 292 women and n = 219 men). 24673294

2014

Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.600 Biomarker PSYGENET Polymorphism of circadian clock genes and temperamental dimensions of the TEMPS-A in bipolar disorder. 24679394

2014

Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.600 Biomarker PSYGENET Since stressful life events or increased vulnerability to stress are risk factors for multiple psychiatric disorders, including post-traumatic stress disorder (PTSD), attention deficit hyperactivity disorder (ADHD), bipolar disorder (BD), major depressive disorder (MDD), alcohol use disorder (AUD) and schizophrenia (SCZ), we propose that modulation of the stress response is a common mechanism by which circadian clock genes affect these illnesses. 25135782

2014