Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker PSYGENET The present study investigated the potential therapeutic utility of combining a 5-HT7 antagonist with a selective serotonin (5-HT) reuptake inhibitor (SSRI), the standard of care in depression, on circadian rhythm regulation. 23276605

2013
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker PSYGENET The serotonin 5-HT(7) receptor has been linked to various psychiatric disorders, including schizophrenia, anxiety and depression, and is antagonized by antipsychotics such as risperidone, clozapine and lurasidone. 22843252

2012
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099

2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker PSYGENET The data furthermore support the hypothesis that the 5-HT(7) receptor might be a suitable target for treating depression. 20097233

2010
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker PSYGENET There is a considerable amount of evidence supporting a role for the 5-HT(7) receptor in depression. 19649616

2009
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.530 Biomarker PSYGENET As roles for 5-HT7 receptors in anxiety and depression were recently established, the current findings have implications for understanding the high anxiety and depressive-like phenotype of SERT-deficient mice. 18712364

2008