Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.530 Biomarker PSYGENET These results support our hypothesis that reelin plays a role in the pathogenesis of depression and suggest that reelin could be an important target for the development of novel therapeutics for the treatment of depression. 23608736

2013

Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.530 Biomarker PSYGENET In addition, we demonstrate that while stress increased NMDA NR2B-mediated synaptic transmission, known to be implicated in depression, Reelin overexpression significantly reduced it. 21814183

2011

Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.530 Biomarker PSYGENET Corticosterone produced dose-dependent increases in depression-like behavior and decreases in reelin expression, neurogenesis, and cell maturation regardless of mouse genotype. 20849864

2011

Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.530 Biomarker PSYGENET In addition, reelin protein in the molecular layer of the dentate gyrus was decreased in schizophrenia, bipolar disorder, and depression at the trend level of statistical significance (P=0.065). 14708030

2004

Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.530 Biomarker CTD_human In addition, reelin protein in the molecular layer of the dentate gyrus was decreased in schizophrenia, bipolar disorder, and depression at the trend level of statistical significance (P=0.065). 14708030

2004