Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET Our results confirm that the risk of depression conferred by childhood maltreatment is modified by variation at both SERT and BDNF genes. 25510949

2015

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET Pregabalin showed the analgesic effects but had no effects on either depression or the BDNF pathway. 25283187

2015

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. 25422957

2014

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET We present here the current knowledge regarding the relation between chronic stress, BDNF and NMDARs and its implications in depression. 25277075

2014

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287

2012

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Therapeutic CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287

2012

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET These findings support the 'differential-susceptibility' hypothesis, whereby the BDNF Val allele modulates the influence of environmental stress on depression by enhancing the neuroplastic response to all life events. 22931410

2012

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker CTD_human Repeated electroconvulsive stimuli increase brain-derived neurotrophic factor in ACTH-treated rats. 16330021

2006

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Therapeutic CTD_human Repeated electroconvulsive stimuli increase brain-derived neurotrophic factor in ACTH-treated rats. 16330021

2006