Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. 27737899

2016

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. 27737899

2016

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Granulocyte colony-stimulating factor (G-CSF) and pegylated G-CSF (peg-G-CSF) have been approved by the U.S. Food and Drug Administration as hematopoietic growth factors to treat chemotherapy-induced neutropenia. 16761898

2006

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Granulocyte colony-stimulating factor (G-CSF) and pegylated G-CSF (peg-G-CSF) have been approved by the U.S. Food and Drug Administration as hematopoietic growth factors to treat chemotherapy-induced neutropenia. 16761898

2006

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Neoadjuvant and adjuvant chemotherapy with doxorubicin and docetaxel in locally advanced breast cancer. 15585077

2004

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Neoadjuvant and adjuvant chemotherapy with doxorubicin and docetaxel in locally advanced breast cancer. 15585077

2004

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Docetaxel and epirubicin supported by granulocyte colony-stimulating factor first-line in advanced breast cancer. 12926135

2003

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Docetaxel and epirubicin supported by granulocyte colony-stimulating factor first-line in advanced breast cancer. 12926135

2003

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Neutropenia was a dose limiting factor with half of the cases (7/14) presenting with severe neutropenia (grade 3-4), but a response was observed in all of them on administration of G-CSF. 12884814

2003

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Neutropenia was a dose limiting factor with half of the cases (7/14) presenting with severe neutropenia (grade 3-4), but a response was observed in all of them on administration of G-CSF. 12884814

2003

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours. 12085204

2002

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours. 12085204

2002

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Five patients experienced febrile neutropenia, which was successfully treated with G-CSF and broad-spectrum antibiotics. 11712802

2001

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Five patients experienced febrile neutropenia, which was successfully treated with G-CSF and broad-spectrum antibiotics. 11712802

2001

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human All patients received granulocyte colony-stimulating factor (G-CSF) beginning on the day after paclitaxel and lasting until recovery from neutropenia. 9774950

1998

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Phase I study of paclitaxel (taxol) and granulocyte colony stimulating factor (G-CSF) in patients with unresectable malignancy. 9740541

1998

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human All patients received granulocyte colony-stimulating factor (G-CSF) beginning on the day after paclitaxel and lasting until recovery from neutropenia. 9774950

1998

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Phase I study of paclitaxel (taxol) and granulocyte colony stimulating factor (G-CSF) in patients with unresectable malignancy. 9740541

1998

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human High-dose paclitaxel with granulocyte colony-stimulating factor in patients with advanced breast cancer refractory to anthracycline therapy: a European Cancer Center trial. 7543699

1995

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Hemotoxicity by prolonged etoposide administration to mice can be prevented by simultaneous growth factor therapy. 7529132

1995

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human High-dose paclitaxel with granulocyte colony-stimulating factor in patients with advanced breast cancer refractory to anthracycline therapy: a European Cancer Center trial. 7543699

1995

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human Hemotoxicity by prolonged etoposide administration to mice can be prevented by simultaneous growth factor therapy. 7529132

1995

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Biomarker CTD_human A phase I trial of 3-hour infusions of paclitaxel (Taxol) with or without granulocyte colony-stimulating factor. 7524159

1994

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human A phase I trial of 3-hour infusions of paclitaxel (Taxol) with or without granulocyte colony-stimulating factor. 7524159

1994

Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.400 Therapeutic CTD_human Granulocyte colony stimulating factor (G-CSF) for mustard-induced bone marrow suppression. 7688884

1993