Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker PSYGENET Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression. 25650523

2015

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker PSYGENET Our study included 2679 participants.Those with both the 5-HTTLPR s allele and the BDNF Met allele showed the highest risk of MD if they had previously experienced emotional (z = 2.08, p = 0.037), sexual (z = 2.19, p = 0.029) or any kind of childhood abuse (z = 2.37, p = 0.018). 25510949

2015

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker PSYGENET Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response. 24679990

2014

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker PSYGENET Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. 24972302

2014

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker PSYGENET Association between serotonin transporter genotype, brain structure and adolescent-onset major depressive disorder: a longitudinal prospective study. 25226554

2014

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker CTD_human Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. 21843009

2011

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677

2009

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker CTD_human The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure. 18686203

2008

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.600 Biomarker CTD_human Regional serotonin transporter availability and depression are correlated in Wilson's disease. 12898347

2003