Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.600 Biomarker CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542

2011

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.600 Biomarker CTD_human Breast cancer cell lines with FGFR1 overexpression and amplification show enhanced ligand-dependent signaling, with increased activation of the mitogen-activated protein kinase and phosphoinositide 3-kinase-AKT signaling pathways in response to FGF2, but also show basal ligand-independent signaling, and are dependent on FGFR signaling for anchorage-independent growth. 20179196

2010

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.600 GenomicAlterations CGI