DisGeNET - a database of gene-disease associations

Source: GWASDB

Disease: Age related macular degeneration ×

Gene: CYP21A2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.

23577725

2013

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Seven new loci associated with age-related macular degeneration.

23455636

2013

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

22705344

2012

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.

22694956

2012

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.

21909106

2011

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.

21665990

2011

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

20385819

2010

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

20385826

2010

Entrez Id:	1589
Gene Symbol:	CYP21A2

CYP21A2

CUI:	C0242383
Disease:	Age related macular degeneration

Age related macular degeneration

0.100

GeneticVariation

GWASDB

Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.

20861866

2010