Source: ALL

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1217691063
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.100 0.909 11 2000 2019
dbSNP: rs1799983
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2011 2011
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.100 0.967 30 2006 2020
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 1.000 5 2006 2019
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.100 1.000 26 2006 2020
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2004 2004
dbSNP: rs1801133
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.020 1.000 2 2013 2014
dbSNP: rs1800629
rs1800629
TNF
0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2016 2016
dbSNP: rs1800795
rs1800795
IL6 ; STEAP1B ; IL6-AS1
0.494 0.840 7 22727026 intron variant C/G snv 0.71
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.020 1.000 2 2016 2016
dbSNP: rs1805087
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.020 1.000 2 2007 2017
dbSNP: rs1801282
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 1.000 6 2008 2019
dbSNP: rs1805192
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 1.000 6 2008 2019
dbSNP: rs2275913
rs2275913
IL17A
0.514 0.760 6 52186235 upstream gene variant G/A snv 0.28
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2013 2013
dbSNP: rs1801131
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2014 2014
dbSNP: rs9939609
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2011 2011
dbSNP: rs1061170
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2011 2011
dbSNP: rs1229984
rs1229984
ADH1B
0.570 0.560 4 99318162 missense variant T/C;G snv 0.90
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2014 2014
dbSNP: rs34637584
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.070 0.857 7 2010 2020
dbSNP: rs9340799
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2009 2009
dbSNP: rs429358
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2019 2019
dbSNP: rs121912438
rs121912438
SOD1
0.605 0.520 21 31667299 missense variant G/A;C;T snv 1.2E-05; 8.0E-06
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2008 2008
dbSNP: rs121912651
rs121912651
TP53
0.605 0.680 17 7674221 missense variant G/A;C snv 4.0E-06
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.700 0
dbSNP: rs104893877
rs104893877
SNCA
0.614 0.360 4 89828149 missense variant C/T snv
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 1.000 3 2013 2018
dbSNP: rs2236225
rs2236225
MTHFD1
0.614 0.640 14 64442127 missense variant G/A snv 0.44 0.38
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.010 1.000 1 2014 2014
dbSNP: rs368869806
rs368869806
PTCH1
0.614 0.480 9 95485875 splice acceptor variant C/T snv 4.0E-06 7.0E-06
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.700 0