Source: BEFREE

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs118204073
rs118204073
LPL
0.925 0.120 8 19951825 missense variant A/C snv 4.0E-06 7.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1993 1993
dbSNP: rs1801278
rs1801278
IRS1
0.637 0.560 2 226795828 missense variant C/G;T snv 4.0E-06; 5.2E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.841 44 1994 2019
dbSNP: rs1801276
rs1801276
IRS1
0.882 0.160 2 226797205 missense variant C/G snv 1.4E-02 1.3E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.060 0.833 6 1994 2011
dbSNP: rs4994
rs4994
ADRB3
0.578 0.640 8 37966280 missense variant A/G snv 0.11 9.2E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.882 34 1995 2017
dbSNP: rs1801483
rs1801483
GCGR
0.851 0.160 17 81809839 missense variant G/A snv 7.4E-03 6.3E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.538 13 1995 2005
dbSNP: rs2229621
rs2229621
HK2
1.000 0.080 2 74872350 missense variant A/T snv 0.18 0.19
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 1.000 2 1995 1996
dbSNP: rs662
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 1.000 12 1996 2019
dbSNP: rs1466929132
rs1466929132
IAPP ; SLCO1A2
0.925 0.200 12 21378325 missense variant G/A;C snv 4.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.050 1.000 5 1996 2019
dbSNP: rs1037733674
rs1037733674
GCG ; LOC101929532
0.882 0.120 2 162147429 missense variant T/C snv 1.4E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 0.500 4 1996 2002
dbSNP: rs1047711865
rs1047711865
ZNF236 ; LOC105372214
1.000 0.080 18 76849628 missense variant A/G;T snv 4.1E-06; 4.1E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs1251901596
rs1251901596
ZNF236 ; LOC105372214
1.000 0.080 18 76849634 missense variant A/G snv 4.1E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs1799904
rs1799904
PCSK1 ; LOC101929710
1.000 0.080 5 96429259 missense variant C/A;T snv 4.0E-06; 2.1E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs1801118
rs1801118
IRS1
1.000 0.080 2 226798113 missense variant A/G snv 5.6E-05 2.1E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs1801120
rs1801120
IRS1
1.000 0.080 2 226796313 missense variant G/A snv 4.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs6234
rs6234
PCSK1 ; LOC101929710
0.851 0.160 5 96393270 missense variant G/C snv 0.27 0.24
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs756025720
rs756025720
INSR
1.000 0.080 19 7142929 missense variant G/A snv 8.0E-06 7.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs778869893
rs778869893
ZNF236
1.000 0.080 18 76904406 missense variant C/G snv 1.6E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 1996 1996
dbSNP: rs1801282
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 0.902 118 1997 2018
dbSNP: rs1805192
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.893 103 1997 2018
dbSNP: rs1232898090
rs1232898090
PPARA
0.637 0.600 22 46198429 missense variant G/C;T snv 4.0E-06; 4.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.762 21 1997 2018
dbSNP: rs699
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 0.933 15 1997 2017
dbSNP: rs757110
rs757110
ABCC8
0.851 0.080 11 17396930 missense variant C/A;T snv 0.64; 8.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.790 0.900 9 1997 2018
dbSNP: rs1267969615
rs1267969615
ACE
0.532 0.760 17 63490960 missense variant T/C snv 4.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.070 0.857 7 1997 2010
dbSNP: rs4762
rs4762
AGT
0.637 0.440 1 230710231 missense variant G/A snv 0.12 0.11
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 0.750 4 1997 2017
dbSNP: rs5447
rs5447
GYS1
1.000 0.080 19 48977986 missense variant T/C snv 1.9E-02 1.4E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 0.500 4 1997 2003