rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis aimed to summarize published data about the association between two SNPs of XRCC1 (Arg194Trp and Arg399Gln) and treatment outcomes of patients with advanced gastric cancer.
|
24465544 |
2014 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings demonstrated that the genetic variant Arg280His in XRCC1 may contribute to cancer progression and that XRCC1 Arg194Trp variants may act as a favorable prognostic indicator of resected GC, particularly among the diffuse-type GC.
|
23425027 |
2013 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
However, significant associations between Arg194Trp polymorphism and gastric cancer were found in Asian.
|
25335737 |
2014 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models.
|
20817763 |
2010 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group 1 (XRCC1, Arg194Trp and Arg399Gln), adenosine diphosphate ribosyl transferase (ADPRT, Val762Ala), 8-oxoguanine DNA glycosylase (OGG1, Ser326Cys) and apurinic/apyrimidinic endonuclease 1 (APE1, Asp148Glu) and evolution of H.pylori-associated precancerous gastric lesions, a population-based cohort study was conducted in Linqu County, a high-risk area of gastric cancer in China.
|
19147860 |
2009 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, XRCC1 Arg194Trp homozygous mutant genotype (Trp/Trp) was found to be associated with increased risk of GC.
|
21604176 |
2012 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, we suggest that the XRCC1 gene Arg194Trp polymorphism is associated with gastric cancer susceptibility in the Chinese population.
|
27706710 |
2016 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
In particular, individuals with the XRCC1 Arg194Trp variant genotype are at increased risk for GC below 60 years old.
|
23317230 |
2012 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China.
|
22901183 |
2012 |
rs1799782
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population.
|
16425350 |
2005 |