rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met.
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20703451 |
2011 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
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15459944 |
2005 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
Our data demonstrate that in patients with psychoses, met carriers of the BDNF val66met with high level of childhood abuse have more cognitive and brain abnormalities than all other groups.
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23876786 |
2013 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
We investigated the influence of childhood abuse and neglect on positive and negative psychotic-like experiences in adulthood and the potential moderating effect of the BDNF-Val66Met polymorphism.
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21719879 |
2011 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
Significant four-way interactions were found for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × family conflicts and for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × sexual abuse.
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25522433 |
2014 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
In conclusion, BDNF val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status.
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22832736 |
2012 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
This result suggests that Val66Met modulates the effect of childhood sexual abuse on the violence of SB.
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17883407 |
2008 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse.
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21996278 |
2012 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
In this study we analysed modulating effects of BDNF Val(66)Met polymorphism on the effects of physical maltreatment, rape and childhood sexual abuse on impulsive aggression.
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19817874 |
2010 |
rs759834365
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Drug abuse
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0.100 |
GeneticVariation
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BEFREE |
However, whether the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism participates in the childhood-abuse influenced schizophrenic symptoms remains unclear.
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29595641 |
2018 |