|
rs876661222
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
CATTA |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs876660943
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs864622153
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs786201050
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
TG |
0.700 |
GeneticVariation
|
CLINVAR |
Population-based molecular screening for Lynch syndrome: implications for personalized medicine.
|
23733757 |
2013 |
|
rs786201050
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
TG |
0.700 |
GeneticVariation
|
CLINVAR |
Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.
|
28944238 |
2017 |
|
rs786201042
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs63751319
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.
|
16807412 |
2006 |
|
rs63751319
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts.
|
18269114 |
2008 |
|
rs63750617
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs63750119
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
|
24763289 |
2014 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
|
24362816 |
2014 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
|
22949379 |
2013 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
|
25559809 |
2015 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
|
25980754 |
2015 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Feasibility of screening for Lynch syndrome among patients with colorectal cancer.
|
18809606 |
2008 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts.
|
27273229 |
2017 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
|
rs587779227
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study.
|
26552419 |
2015 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer.
|
17453009 |
2007 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
|
20028993 |
2010 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population.
|
24728189 |
2014 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function.
|
21836479 |
2011 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
|
18566915 |
2009 |
|
rs267608122
|
|
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
|
A |
0.700 |
GeneticVariation
|
CLINVAR |
Familial endometrial cancer in female carriers of MSH6 germline mutations.
|
10508506 |
1999 |