rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the present study, we have examined a large study population to determine whether the C677T polymorphism at the MTHFR locus affects susceptibility for cervical cancer or its precursor, cervical intraepithelial neoplasia (CIN).
|
15635481 |
2005 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association between Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer: a meta-analysis.
|
23431363 |
2013 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study indicated that the MTHFR C677T may be no associated with cervical cancer risk, and yet the MTHFR A1298C polymorphism may be a risk factor for cervical cancer.
|
26879954 |
2016 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
However, the MTHFR C677T polymorphism was not associated with the risk of cervical cancer or CIN.
|
29740106 |
2018 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis supports an association between MTHFR 677C>T polymorphism and cervical cancer, and the effect of this association may be race specific.
|
23057736 |
2012 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that White women with mutant C677T genotypes might have a lower risk of cervical cancer, yet lacking enough statistical robustness.
|
23029458 |
2012 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Cervical cancer with polymorphism in MTHFR C677T gene: a systematic review and meta-analysis.
|
23070908 |
2013 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR C677T and A1298C polymorphisms and cervical carcinoma susceptibility: meta-analyses based on 4,421 individuals.
|
22711309 |
2012 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
C677T polymorphism of MTHFR gene may increase the risk of cervical cancer in the complete over-dominant model.
|
23490201 |
2013 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR C677T polymorphism was not associated with cervical cancer and HPV infection.
|
31170928 |
2019 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
|
15581963 |
2004 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The MTHFR C677T polymorphism is associated with cervical cancer risk in Asians, while any possible link in the Caucasian population needs further studies.
|
22901193 |
2012 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
No effects of MTHFR C677T polymorphism on CIN II/III risk and MTHFR A1298C or MS A2756G polymorphisms on cervical cancer risk were detected.
|
23864153 |
2013 |
rs1217691063
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Combination analysis of MTHFR C677T and A1298C polymorphisms revealed that combined MTHFR 677CC and 1298CC are strongly associated with a risk of cervical cancer.
|
27771518 |
2016 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
This study indicated that the MTHFR C677T may be no associated with cervical cancer risk, and yet the MTHFR A1298C polymorphism may be a risk factor for cervical cancer.
|
26879954 |
2016 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
In summary, this meta-analysis suggests that MTHFR A1298C polymorphism is associated with increased cervical cancer and lymphoma risk in Asians, and MTHFR A1298C polymorphism is associated with decreased colorectal cancer risk in Asians.
|
26156333 |
2016 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
It can be concluded that A1298C polymorphism is a genetic risk factor for cervical cancer in the assessed Iranian population group.
|
27771518 |
2016 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
In contrast, the MTHFR A1298C polymorphism could increase the risk of both cervical cancer and CIN.
|
29740106 |
2018 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
No effects of MTHFR C677T polymorphism on CIN II/III risk and MTHFR A1298C or MS A2756G polymorphisms on cervical cancer risk were detected.
|
23864153 |
2013 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The marginal association between the MTHFR A1298C polymorphisms and the susceptibility to cervical cancer requires a further study.
|
23285018 |
2012 |
rs397507444
|
|
Cervix carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
MTHFR C677T and A1298C polymorphisms and cervical carcinoma susceptibility: meta-analyses based on 4,421 individuals.
|
22711309 |
2012 |
rs768873896
|
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.
|
16875718 |
2006 |
rs55763075
|
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
PCR-DNA analysis was used to explore the genotype of the SNPs (rs4846048 and rs55763075) of the MTHFR 3'-UTR as well as the association between allelic frequencies and the CC risk.
|
31750632 |
2020 |
rs4846048
|
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The preliminary report revealed that the SNP rs4846048 of MTHFR enhanced the risk of CC through association with miR-522, which further regulated cell viability and apoptosis in Hela cells.
|
31750632 |
2020 |