DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Malignant neoplasm of prostate ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs864622007

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.830

GeneticVariation

CLINVAR

dbSNP:

rs864622007

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.830

GeneticVariation

UNIPROT

dbSNP:

rs6983267

POU5F1B ; CASC8 ; PCAT1 ; CCAT2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies.

24753544

2014

dbSNP:

rs6983267

POU5F1B ; CASC8 ; PCAT1 ; CCAT2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

A combined analysis with four additional studies (total: 4,296 cases and 4,299 controls) confirms association with prostate cancer for rs6983267 in the centromeric locus (P = 9.42 x 10(-13); heterozygote odds ratio (OR): 1.26, 95% confidence interval (c.i.): 1.13-1.41; homozygote OR: 1.58, 95% c.i.: 1.40-1.78).

17401363

2007

dbSNP:

rs6983267

POU5F1B ; CASC8 ; PCAT1 ; CCAT2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

23555315

2013

dbSNP:

rs6983267

POU5F1B ; CASC8 ; PCAT1 ; CCAT2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple loci identified in a genome-wide association study of prostate cancer.

18264096

2008

dbSNP:

rs6983267

POU5F1B ; CASC8 ; PCAT1 ; CCAT2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple newly identified loci associated with prostate cancer susceptibility.

18264097

2008

dbSNP:

rs4430796

HNF1B

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple loci identified in a genome-wide association study of prostate cancer.

18264096

2008

dbSNP:

rs4430796

HNF1B

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple newly identified loci associated with prostate cancer susceptibility.

18264097

2008

dbSNP:

rs2735839

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple newly identified loci associated with prostate cancer susceptibility.

18264097

2008

dbSNP:

rs16901979

PCAT1 ; CASC19

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility.

19767754

2009

dbSNP:

rs16901979

PCAT1 ; CASC19

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

23555315

2013

dbSNP:

rs16901979

PCAT1 ; CASC19

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

17401366

2007

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

23555315

2013

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

17401366

2007

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple newly identified loci associated with prostate cancer susceptibility.

18264097

2008

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.

17401363

2007

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility.

19767754

2009

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Multiple loci identified in a genome-wide association study of prostate cancer.

18264096

2008

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Evaluating genetic risk for prostate cancer among Japanese and Latinos.

22923026

2012

dbSNP:

rs1447295

CASC8

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

GWASDB

Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies.

24753544

2014

dbSNP:

rs138213197

HOXB13

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

UNIPROT

dbSNP:

rs137852603

MXI1

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

UNIPROT

NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology.

22138009

2011

dbSNP:

rs137852603

MXI1

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

UNIPROT

A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment.

25394175

2015

dbSNP:

rs137852603

MXI1

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.800

GeneticVariation

UNIPROT

Early detection of prostate cancer: AUA Guideline.

23659877

2013