Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs854560
rs854560
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation BEFREE However, it was observed a significant association of PON1 rs662 (Q192R) variant genotype (RR) with retinoblastoma (OR = 4.08, 95 % CI 1.13-14.97), whereas the PON1 rs854560 (L55M) polymorphism was not associated with any tumor. 24972570

2014

dbSNP: rs854560
rs854560
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation BEFREE In conclusion, our results suggest that the M allele of L55M polymorphism could be a suitable marker for BC susceptibility and tumor prognosis in Egyptian women. 21229382

2011

dbSNP: rs854560
rs854560
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation BEFREE In summary, this meta-analysis proved that <i>PON1</i> rs854560 polymorphism could be used to identify individual with elevated susceptibility to cancer, especially for haematological tumours and breast cancer. 31762361

2019

dbSNP: rs854560
rs854560
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation BEFREE These results indicate that PON1 L55M genetic polymorphisms may be associated with the risk of breast cancer and could potentially serve as useful genetic markers for tumor prognosis in some populations of Chinese women. 28445984

2017