Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.040 GeneticVariation BEFREE After adjusting for age, the IL6 -634G > C (rs1800796) allele showed association with osteoporosis (odds ratio (OR) for CC + CG = 2.51, p = 0.0047)), independent of statin use or smoking status. 19506792

2010
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.040 GeneticVariation BEFREE In men, we detected significant interactions of IL-6 rs1800796 with LEPR rs1805096 and rs1892534 for FN and TH OST (all p < 0.05). 27401061

2016
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.040 GeneticVariation BEFREE Our results suggested that the C allele of rs1800796 and the C allele of rs2069849 of IL-6 gene interaction between rs1800796 and abdominal obesity were all associated with increased OST risk. 31301734

2019
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.040 GeneticVariation BEFREE Using the meta-analysis approach, the present study is designed to provide a relatively comprehensive picture of the relationship between bone mineral density (BMD) or osteoporosis and polymorphisms in the promoter region of IL-6 (rs1800795 and rs1800796). 23760743

2014