| Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
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A | 0.900 | CausalMutation | CLINVAR | ||||||||||
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A | 0.700 | GeneticVariation | CLINVAR | ||||||||||
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T | 0.700 | CausalMutation | CLINVAR | ||||||||||
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T | 0.700 | GeneticVariation | CLINVAR | ||||||||||
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G | 0.700 | CausalMutation | CLINVAR | ||||||||||
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T | 0.700 | CausalMutation | CLINVAR | ||||||||||
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T | 0.700 | CausalMutation | CLINVAR | ||||||||||
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T | 0.700 | GeneticVariation | CLINVAR | ||||||||||
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C | 0.700 | GeneticVariation | CLINVAR | ||||||||||
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G | 0.700 | CausalMutation | CLINVAR | ||||||||||
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A | 0.700 | CausalMutation | CLINVAR | ||||||||||
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T | 0.700 | GeneticVariation | CLINVAR | ||||||||||
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T | 0.700 | CausalMutation | CLINVAR | ||||||||||
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A | 0.700 | CausalMutation | CLINVAR | ||||||||||
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0.010 | GeneticVariation | BEFREE | <i>ELOVL5</i> rs2397142 was significantly associated with eczema (<i>P</i> = 0.011) and methylation at cg11748354 and cg24524396 (<i>P</i> < 0.001 and <i>P</i> = 0.036, respectively). | 31244960 | 2019 |
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0.010 | GeneticVariation | BEFREE | C1014T SNP of CCR4 does not appear to be associated with susceptibility to atopic dermatitis in Japanese patients. | 15202833 | 2004 |
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0.070 | GeneticVariation | BEFREE | G1258A polymorphism in SPINK5 may be associated with atopic dermatitis, which shares several clinical features with NS. | 19438860 | 2009 |
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0.010 | GeneticVariation | BEFREE | A case-control study was performed to determine whether rs77152992 and rs1058808 are candidate risk factors for early-onset AD. rs77152992 was significantly associated with early-onset AD (odds ratio [OR], 0.42; 95% confidence interval [CI], 0.21~0.83; <i>p</i>=0.0133) in allele frequencies. | 29853740 | 2018 |
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G | 0.700 | CausalMutation | CLINVAR | A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review. | 26789910 | 2016 |
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0.710 | GeneticVariation | BEFREE | A functional amino acid change in the IL-6 receptor (IL-6R Asp358Ala; rs2228145) was significantly associated with AD (odds ratio [OR], 1.15; P = 5 × 10(-9)). | 23582566 | 2013 |
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0.010 | GeneticVariation | BEFREE | A significant association was detected between rs3745367 and atopic dermatitis with age and gender specificity (<i>p</i> < 0.05), while no significant association between rs3219177 and atopic dermatitis was found (<i>p</i> > 0.05). | 29584687 | 2018 |
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0.010 | GeneticVariation | BEFREE | After adjustment for FLG effects, a significant epistatic effect of the FCER1A variants rs10489854 and rs2511211 on eczema risk was detected. | 20028371 | 2010 |
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0.010 | GeneticVariation | BEFREE | After adjustment for FLG effects, a significant epistatic effect of the FCER1A variants rs10489854 and rs2511211 on eczema risk was detected. | 20028371 | 2010 |
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0.040 | GeneticVariation | BEFREE | After stratifying by phthalate metabolite levels, FLG P478S TT genotype was related to a higher odds of AD in children with high MBP levels (aOR=4.74, 95% CI 1.45-15.5) and in children with high MBzP levels (aOR=3.46, 95%CI 1.03-11.58). | 25460639 | 2015 |
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0.010 | GeneticVariation | BEFREE | After stratifying by phthalate metabolite levels, FLG P478S TT genotype was related to a higher odds of AD in children with high MBP levels (aOR=4.74, 95% CI 1.45-15.5) and in children with high MBzP levels (aOR=3.46, 95%CI 1.03-11.58). | 25460639 | 2015 |