Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2237892
rs2237892
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.900 GeneticVariation GWASDB The association of KCNQ1 with type 2 diabetes was replicated in populations of Korean, Chinese and European ancestry as well as in two independent Japanese populations, and meta-analysis with a total of 19,930 individuals (9,569 cases and 10,361 controls) yielded a P value of 1.7 x 10(-42) (OR = 1.40; 95% CI = 1.34-1.47) for rs2237892. 18711367

2008
dbSNP: rs2237897
rs2237897
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.880 GeneticVariation GWASDB The association of these SNPs with type 2 diabetes was replicated in samples from Singaporean (additive model: rs2237895, P = 8.5 x 10(-3); OR = 1.14, rs2237897, P = 2.4 x 10(-4); OR = 1.22) and Danish populations (additive model: rs2237895, P = 3.7 x 10(-11); OR = 1.24, rs2237897, P = 1.2 x 10(-4); OR = 1.36). 18711366

2008
dbSNP: rs2237892
rs2237892
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.900 GeneticVariation GWASDB Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009
dbSNP: rs2074238
rs2074238
KCNQ1
CUI: C0429028
Disease: QT interval feature (observable entity)
QT interval feature (observable entity) 		T 0.800 GeneticVariation GWASDB Common variants at ten loci influence QT interval duration in the QTGEN Study. 19305408

2009
dbSNP: rs16928297
rs16928297
KCNQ1
CUI: C0429028
Disease: QT interval feature (observable entity)
QT interval feature (observable entity) 		0.800 GeneticVariation GWASDB Common variants at ten loci modulate the QT interval duration in the QTSCD Study. 19305409

2009
dbSNP: rs12576239
rs12576239
KCNQ1
CUI: C0429028
Disease: QT interval feature (observable entity)
QT interval feature (observable entity) 		T 0.800 GeneticVariation GWASDB Common variants at ten loci influence QT interval duration in the QTGEN Study. 19305408

2009
dbSNP: rs12296050
rs12296050
KCNQ1
CUI: C0429028
Disease: QT interval feature (observable entity)
QT interval feature (observable entity) 		T 0.800 GeneticVariation GWASDB Common variants at ten loci modulate the QT interval duration in the QTSCD Study. 19305409

2009
dbSNP: rs2237895
rs2237895
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.900 GeneticVariation GWASDB We also confirmed that variants in KCNQ1 were associated with T2D risk, with the strongest signal at rs2237895 (P = 9.65x10(-10); OR = 1.29, 95% CI = 1.19-1.40). 20174558

2010
dbSNP: rs2237892
rs2237892
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. 20818381

2010
dbSNP: rs2237897
rs2237897
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.880 GeneticVariation GWASDB A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. 20174558

2010
dbSNP: rs231362
rs231362
KCNQ1 ; KCNQ1OT1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.840 GeneticVariation GWASDB Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827

2010
dbSNP: rs163184
rs163184
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.810 GeneticVariation GWASDB A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. 20818381

2010
dbSNP: rs163177
rs163177
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.810 GeneticVariation GWASDB A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. 20174558

2010
dbSNP: rs234853
rs234853
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. 20818381

2010
dbSNP: rs2237886
rs2237886
KCNQ1
CUI: C0489786
Disease: Height
Height 		T 0.700 GeneticVariation GWASDB Hundreds of variants clustered in genomic loci and biological pathways affect human height. 20881960

2010
dbSNP: rs163171
rs163171
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. 20818381

2010
dbSNP: rs2237892
rs2237892
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700

2011
dbSNP: rs2237892
rs2237892
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs2237896
rs2237896
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs163184
rs163184
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs163182
rs163182
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.810 GeneticVariation GWASDB A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese. 21799836

2011
dbSNP: rs234857
rs234857
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 21874001

2011
dbSNP: rs234853
rs234853
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs234852
rs234852
KCNQ1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs2237897
rs2237897
KCNQ1
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.700 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011