Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9274407
rs9274407
HLA-DQB1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
dbSNP: rs9274407
rs9274407
HLA-DQB1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
dbSNP: rs6582630
rs6582630
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs6582630
rs6582630
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs3129900
rs3129900
TSBP1 ; TSBP1-AS1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. 20639878

2010
dbSNP: rs3129900
rs3129900
TSBP1 ; TSBP1-AS1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. 20639878

2010
dbSNP: rs2523822
rs2523822
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
dbSNP: rs2523822
rs2523822
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
dbSNP: rs2395029
rs2395029
HCP5
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles. 30661239

2019
dbSNP: rs2395029
rs2395029
HCP5
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs2395029
rs2395029
HCP5
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs1497546
rs1497546
LOC105373999
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs1497546
rs1497546
LOC105373999
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs10937275
rs10937275
ST6GAL1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs10937275
rs10937275
ST6GAL1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs10812428
rs10812428
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASDB HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs10812428
rs10812428
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.800 GeneticVariation GWASCAT HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. 19483685

2009
dbSNP: rs7828135
rs7828135
TPD52
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1*07:01. 25987243

2016
dbSNP: rs73122578
rs73122578
ROBO1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
dbSNP: rs72696020
rs72696020
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
dbSNP: rs72631567
rs72631567
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
dbSNP: rs6694270
rs6694270
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
dbSNP: rs61858823
rs61858823
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
dbSNP: rs6139258
rs6139258
RNF24
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. 28062682

2017
dbSNP: rs597480
rs597480
SYTL2
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017