|
rs1800796
|
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Relationship between polymorphisms in -572G/C interleukin 6 promoter gene polymorphisms (rs1800796) and risk of rheumatoid arthritis: A meta-analysis.
|
31782615 |
2020 |
|
rs1800795
|
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-6 rs1800795, IL-18 rs1946518 and IL-18 rs187238 polymorphisms may confer susceptibility to TB, especially for Asians.
|
31676365 |
2020 |
|
rs1800795
|
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-2 rs2069762, IL-4 rs2243250, IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871 and IL-10 rs1800896 polymorphisms may confer susceptibility to TB, especially for Asians.
|
31669382 |
2020 |
|
rs1800795
|
|
Irritable Bowel Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Ten relevant genes were evaluated.SNPs rs4263839 and rs6478108 of TNFSF15 associated with an increased risk of IBS; IL6 rs1800795 increased the risk for Caucasian IBS patients which diagnosed by Rome III criteria; and IL23R rs11465804 increased the risk for IBS-C patients.
|
31615448 |
2019 |
|
rs1800795
|
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871, IL-10 rs1800872 and IL-10 rs1800896 may confer susceptibility to TB.
|
31560754 |
2019 |
|
rs1800795
|
|
Obesity
|
|
0.020 |
GeneticVariation
|
BEFREE |
Minor alleles of rs1800795 raised and rs1800797 reduced the risk of obesity, while rs1800796 and rs2069845 may not be associated.
|
31472475 |
2019 |
|
rs1800797
|
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Minor alleles of rs1800795 raised and rs1800797 reduced the risk of obesity, while rs1800796 and rs2069845 may not be associated.
|
31472475 |
2019 |
|
rs2069840
|
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest the IL-6 (rs2069840) polymorphism may influence the occurrence of lung cancer in Moroccan patients.
|
31468132 |
2019 |
|
rs2069840
|
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest the IL-6 (rs2069840) polymorphism may influence the occurrence of lung cancer in Moroccan patients.
|
31468132 |
2019 |
|
rs2069840
|
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest the IL-6 (rs2069840) polymorphism may influence the occurrence of lung cancer in Moroccan patients.
|
31468132 |
2019 |
|
rs1800796
|
|
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
|
rs1800795
|
|
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
|
rs2069840
|
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
|
rs2069837
|
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
|
rs1800797
|
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
|
rs1800795
|
|
Ischemic stroke
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our findings indicated that IL-6 rs1800795 polymorphism was significantly associated with individual susceptibility to IS in Asians, but not in Caucasians.
|
31446341 |
2019 |
|
rs1800795
|
|
Cerebral Infarction
|
|
0.020 |
GeneticVariation
|
BEFREE |
Further subgroup analyses showed that IL-6 rs1800795 was significantly associated with IS in Asians in GG versus GC + CC (dominant model, p = .0005, OR = 0.74, 95%CI 0.62-0.88), CC versus GG + GC (recessive model, p = .003, OR = 1.61, 95%CI 1.17-2.21) and G versus C (allele model, p = .01, OR = 0.74, 95%CI 0.58-0.93), whereas IL-10 rs1800896 polymorphism was significantly associated with cerebral infarction (CI) in GG versus GA + AA (dominant model, p = .02, OR = 2.04, 95%CI 1.14-3.64), GA versus GG + AA (overdominant model, p = .03, OR = 0.50, 95%CI 0.27-0.93) and G versus A (allele model, p = .01, OR = 1.92, 95%CI 1.16-3.17).
|
31446341 |
2019 |
|
rs2069837
|
|
Longevity
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
A meta-analysis of genome-wide association studies identifies multiple longevity genes.
|
31413261 |
2019 |
|
rs1800795
|
|
Leukemia, Myelocytic, Acute
|
|
0.010 |
GeneticVariation
|
BEFREE |
We aimed to evaluate the multivariate effect of TNF-α rs361525, rs1800750, rs1800629, IL-10 rs1800896, rs1800872, IL-6 rs1800795, TGF-β1 rs1800470, IFN-γ rs2430561 single nucleotide polymorphisms (SNPs) on AML risk, the multivariate effect of SNPs on overall survival (OS) in AML and the association between the investigated SNPs and prognostic factors in AML.
|
31373163 |
2019 |
|
rs1800795
|
|
Experimental Organism Basal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have found that the presence of C allele in rs1800795 IL-6 gene polymorphism was associated with increased risk of BCC (aOR 1.86; 95% CI 1.22-2.84; p = 0.004).
|
31342143 |
2019 |
|
rs1800795
|
|
Carcinoma, Basal Cell
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have found that the presence of C allele in rs1800795 IL-6 gene polymorphism was associated with increased risk of BCC (aOR 1.86; 95% CI 1.22-2.84; p = 0.004).
|
31342143 |
2019 |
|
rs1800795
|
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Additionally, we found that carriers of the <i>C</i> allele of 174<i>G>C</i> (rs1800795) polymorphism have an increase in the risk of coronary artery disease under the hereditary models assessed in the study.
|
31338006 |
2019 |
|
rs1800795
|
|
Coronary heart disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Additionally, we found that carriers of the <i>C</i> allele of 174<i>G>C</i> (rs1800795) polymorphism have an increase in the risk of coronary artery disease under the hereditary models assessed in the study.
|
31338006 |
2019 |
|
rs1800795
|
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Additionally, we found that carriers of the <i>C</i> allele of 174<i>G>C</i> (rs1800795) polymorphism have an increase in the risk of coronary artery disease under the hereditary models assessed in the study.
|
31338006 |
2019 |
|
rs1800795
|
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using robust data, we found that <i>IL-6</i> (rs1800795) -174<i>G>C</i> gene polymorphism is associated with CVD risk.
|
31338006 |
2019 |