Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE IGF2BP2 variants rs4402960 and rs1470579 were not associated with type 2 diabetes in the present study (P = 0.632 and P = 0.896, respectively). 18430866

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Among the 11 loci examined, 6 were significantly associated with type 2 diabetes in our population by a logistic regression analysis, similar to previously reported results (rs4402960, P = 0.00009; rs10811661, P = 0.0024; rs5219, P = 0.0034; rs1111875, P = 0.0064; rs13266634, P = 0.0073; rs7756992, P = 0.0363). 18162508

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and HHEX (rs1111875) genes were nominally associated with T2DM in our samples. 24736664

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE According to our results, the case-control study and meta-analysis revealed a significant association between the IGF2BP2 rs4402960 variant and type 2 diabetes in Moroccan and Arab populations. 24898818

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The aim of this study was to analyse the association between PPARG rs1801282, PPARGC1A rs8192678, VEGFA rs2010963, ADRA2A rs553668, KCNQ1 rs2237892, SIRT1 rs7896005, IGF2BP2 rs4402960, and UCP3 rs3781907 single nucleotide variants (SNVs) with T2D and metabolic traits in a case-control study of a population from Mexico City. 29800730

2018

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs4402960, P = 0.002; ADIPOQ+276 G>T, P = 0.004; UCP2Ala55Val, P = 0.01; CDKN2AI2B rs3731201, P = 0.02; rs495490, P = 0.02, and rsl 0811661, P = 0.03) were significantly associated with the risk of IFG/IGT/T2DM. 20384434

2010

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individuals with the GT/TT of IGF2BP2 rs4402960, GG/GC of CDKAL1 rs7754840, or CC of KCNJ11 rs5215, which are known to be related to type 2 diabetes in East Asians. 25755232

2015

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We replicated an association between rs4402960 and T2D status, and reported significant associations with anthropometric traits, fasting insulin, HOMA-IR and HOMA-%B. 20627640

2010

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). 22923468

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The present study provided data suggesting that the wild C allele of IGF2BP2 (rs4402960) had a protective effect against T2DM in obese subjects of Chinese Han population. 25062844

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. 22693455

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The IGF2BP2 gene rs1470579 and rs4402960 polymorphisms were associated with T2DM and therapeutic efficacy of pioglitazone in this Chinese population. 25247335

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The present study has replicated the association of IGF2BP2 rs4402960 with T2D in the Czech population and provided data suggesting that IGF2BP2 may have genetic interaction with IGF2 with a protective effect against DN in male patients with T1D. 22770937

2013

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We validate that IGF2BP2 susceptibility variants rs4402960 and rs1470579 associate with T2DM in Lebanese Arabs. 22245690

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE To investigate this inconsistency, we performed a meta-analysis of 35 studies involving a total of 175,965 subjects for two wildly studied polymorphisms (rs4402960 and rs1470579) of the IFG2BP2 to evaluate the effect of IFG2BP2 on genetic susceptibility for T2D. 22015911

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Patients with schizophrenia have an increased prevalence of type 2 diabetes mellitus, and type 2 diabetes mellitus has shown an association with the rs4402960 gene polymorphism in the insulin-like growth factor II messenger RNA (mRNA)-binding protein 2 gene (IGF2BP2). 23656854

2013

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The meta-analysis also showed the association between T2DM and IGF2BP2 (rs1470579 OR of 1.15 (95% CI = 1.10-1.19), P < 0.0001 under an additive model and rs4402960 OR of 1.14 (95% CI = 1.10-1.18), P < 0.0001 under an additive model). 24229666

2013

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. 17827400

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE In our case-control subjects, susceptibility to type 2 diabetes was replicated in TCF7L2 (rs12255372), CDKAL1 (rs7756992, rs7754840), HHEX (rs7923837), IGF2BP2 (rs4402960 and rs1470579), CDKN2A/B (rs10811661), and SLC30A8 (rs13266634). 19033397

2009

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012