Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE In this study, we aimed to determine the importance of -107T/C, 192Q/R and 55L/M polymorphisms of PON1 gene and three PON1 activities (diazoxonase, paraoxonase, arylesterase) as risk factors for ischemic stroke. 19902425

2009

dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE Two of the 11 SNPs (rs662 and rs854560) were contextualized in a meta-analysis of ischemic stroke. 23356507

2013

dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE Overall, no significant association was found between L55M and IS when all studies were pooled nor by subgroup analysis by ethnicity. 26978533

2017

dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE We studied the significance of the Q192R and M55L polymorphisms of the PON1 gene and the C311S polymorphism of the PON2 gene in different etiologies of ischemic stroke. 17406108

2007

dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE We performed a meta-analysis of published studies investigating the association between ischemic stroke and two nonsynonymous PON1 polymorphisms, rs662 (p.Q192R) and rs854560 (p.L55M) in humans. 20856122

2010

dbSNP: rs854560
rs854560
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.060 GeneticVariation BEFREE In summary, this meta-analysis proved that PON1 rs854560 polymorphism could be used to identify individual with elevated susceptibility to IS, whereas rs662 polymorphism could be used to identify individual with elevated susceptibility to CAD. 31302193

2019