Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. 22693455

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700

2011

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. 22693455

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASDB A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
T 1.000 GeneticVariation GWASCAT A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. 17827400

2007

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Among the 11 loci examined, 6 were significantly associated with type 2 diabetes in our population by a logistic regression analysis, similar to previously reported results (rs4402960, P = 0.00009; rs10811661, P = 0.0024; rs5219, P = 0.0034; rs1111875, P = 0.0064; rs13266634, P = 0.0073; rs7756992, P = 0.0363). 18162508

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE IGF2BP2 variants rs4402960 and rs1470579 were not associated with type 2 diabetes in the present study (P = 0.632 and P = 0.896, respectively). 18430866

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE A total of 15 SNPs were genotyped.Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR) = 1.16 (95% confidence interval (CI) 1.05-1.27); P = 4.5 x 10(-3)] in SLC30A8; rs1111875 [OR = 1.27 (95% CI 1.14-1.40); P = 1.4 x 10(-5)] and rs7923837 [OR = 1.27 (95% CI 1.13-1.43); P = 1.0 x 10(-4)] in HHEX; rs10811661 [OR = 1.27 (95% CI 1.15-1.40); P = 1.9 x 10(-6)] in CDKN2B; rs4402960 [OR = 1.23 (95% CI 1.11-1.36); P = 8.1 x 10(-5)] and rs1470579 [OR = 1.18 (95% CI 1.07-1.31); P = 8.3 x 10(-4)] in IGF2BP2; and rs7754840 [OR = 1.28 (95% CI 1.17-1.41); P = 4.5 x 10(-7)] and rs7756992 [OR = 1.27 (95% CI 1.15-1.40); P = 9.8 x 10(-7)] in CDKAL1. 18477659

2008

dbSNP: rs4402960
rs4402960
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE When combined, each additional risk allele from CDKAL1-rs9465871, CDKN2A/B-rs10811661, IGF2BP2-rs4402960, and SLC30A8-rs13266634 increased the risk for type 2 diabetes by 1.24-fold (P = 2.85 x 10(-7)) or for combined IFG/type 2 diabetes by 1.21-fold (P = 6.31 x 10(-11)). 18633108

2008