Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1048943
rs1048943
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 GeneticVariation BEFREE <b>Conclusion.</b> This meta-analysis revealed a clear association between rs104</span>8943 and rs4646903 polymorphisms of the <i>CYP1A1</i> gene but not between CYP1B1 rs10012, rs162549, rs1800440, and rs2551188 polymorphisms and the risk of PCa. 30765615

2019

dbSNP: rs2551188
rs2551188
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 GeneticVariation BEFREE <b>Conclusion.</b> This meta-analysis revealed a clear association between rs1048943 and rs4646903 polymorphisms of the <i>CYP1A1</i> gene but not between CYP1B1 rs10012, rs162549, rs1800440, and rs2551188 polymorphisms and the risk of PCa. 30765615

2019

dbSNP: rs4646903
rs4646903
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <b>Conclusion.</b> This meta-analysis revealed a clear association between rs1048943 and rs4646903 polymorphisms of the <i>CYP1A1</i> gene but not between CYP1B1 rs10012, rs162549, rs1800440, and rs2551188 polymorphisms and the risk of PCa. 30765615

2019

dbSNP: rs2394882
rs2394882
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <b>Conclusion:</b> Our results suggest that rs2394882 is prognostically relevant in prostate cancer, possibly by modulating the expression of the CSC gene <i>POU5F1</i>. 29104488

2017

dbSNP: rs8752
rs8752
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <b>Conclusions:</b> rs8752 in the 3'untranslated region (UTR) of the 15-hydroxyprostaglandin dehydrogenase (<i>HPGD</i>) gene was found to be responsible for the susceptibility to prostate cancer in Chinese individuals. 29187884

2017

dbSNP: rs662
rs662
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.020 GeneticVariation BEFREE <b>Conclusions:</b> We reported by the first time a correlation between rs662 (PON1) and PCa aggressiveness. 31647334

2019

dbSNP: rs1056836
rs1056836
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 GeneticVariation BEFREE <b>RESULTS:</b><i>CYP1B1</i> rs1056836 variant was associated with decreased risk of PCa [odds ratio (OR): 0.80; 95% confidence interval (CI): 0.68-0.99, <i>P</i> = 0.041]. 29344273

2018

dbSNP: rs12611084
rs12611084
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <i>DPF1</i> rs12611084 was inversely associated with ER-negative breast, endometrioid ovarian, and overall and aggressive prostate cancer risk (OR = 0.93; 95% CI = 0.91-0.96; q = 0.005). 28115406

2017

dbSNP: rs2297441
rs2297441
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <i>RTEL1</i> rs2297441 [odds ratio (OR): 1.23; 95% confidence interval (CI): 1.03-1.46, <i>P</i> = 0.021] and rs3208008 (OR: 1.23; 95% CI: 1.03-1.46) were associated with PCa risk. 31762827

2019

dbSNP: rs3208008
rs3208008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE <i>RTEL1</i> rs2297441 [odds ratio (OR): 1.23; 95% confidence interval (CI): 1.03-1.46, <i>P</i> = 0.021] and rs3208008 (OR: 1.23; 95% CI: 1.03-1.46) were associated with PCa risk. 31762827

2019

dbSNP: rs3783553
rs3783553
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE 4-bp insertion/deletion (rs3783553) polymorphism within the 3'UTR of IL1A contributes to the risk of prostate cancer in a sample of Iranian population. 29023981

2018

dbSNP: rs9282858
rs9282858
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 GeneticVariation BEFREE Prostate cancer and BPH were not associated with the alanine-49 to threonine single nucleotide polymorphism and the (TA)n repeat. 16018939

2005

dbSNP: rs780354238
rs780354238
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 GeneticVariation BEFREE Prostate-cancer-associated I260M variant of DNA polymerase beta is a sequence-specific mutator. 16313169

2005

dbSNP: rs1056836
rs1056836
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 GeneticVariation BEFREE Prostate cancer risk and aggressiveness associated with the CYP1B1 4326C/G (Leu432Val) polymorphism: a meta-analysis of 2788 cases and 2968 controls. 22504876

2012

dbSNP: rs137852593
rs137852593
AR
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 GeneticVariation BEFREE R726L androgen receptor mutation is uncommon in prostate cancer families in the united states. 12539229

2003

dbSNP: rs137852593
rs137852593
AR
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 GeneticVariation BEFREE R726L substitution in the hormone binding region of androgen receptor was found in 1 prostate cancer family but no previously uncharacterized germline mutations were detected. 14665948

2004

dbSNP: rs12329760
rs12329760
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 GeneticVariation BEFREE Met160Val polymorphism in the TRMPSS2 gene and risk of prostate cancer in a population-based case-control study. 15065083

2004

dbSNP: rs486907
rs486907
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 GeneticVariation BEFREE Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study. 16054567

2005

dbSNP: rs2279343
rs2279343
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE Lys262Arg polymorphism of the CYP2B6 gene may be a genetic marker for evaluating the risk of sporadic prostate cancer in native Japanese men. 19425200

2009

dbSNP: rs1800562
rs1800562
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.020 GeneticVariation BEFREE C282Y/H63D compound heterozygotes were not at increased risk for colorectal cancer (HR = 1.27; 95% CI = 0.80, 2.01), breast cancer (HR = 1.16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70). 20099304

2010

dbSNP: rs10993994
rs10993994
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.800 GeneticVariation BEFREE rs10993994 in MSMB promoter affects serum MSMB expression, contributes to the genetic predisposition to prostate cancer in southern Chinese Han population. 20333697

2010

dbSNP: rs4986791
rs4986791
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 GeneticVariation BEFREE Thr399Ile also may be connected with gallbladder cancer, and both of these polymorphisms apparently have no impact on risk of prostate cancer. 21081146

2011

dbSNP: rs351855
rs351855
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.080 GeneticVariation BEFREE Gly-388Arg polymorphism of FGFR-4 most likely contributes to susceptibility to prostate cancer, especially in men of European descent. 21625079

2011

dbSNP: rs1217691063
rs1217691063
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 GeneticVariation BEFREE C677T of the MTHFR gene may provide protective effects on susceptibility to prostate cancer risk. 22370724

2012

dbSNP: rs138213197
rs138213197
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.800 GeneticVariation BEFREE G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis. 24026887

2014