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rs5361
|
|
Simple renal cyst
|
|
0.010 |
GeneticVariation
|
BEFREE |
The role of serum E-selectin level and E-selectin gene S128R polymorphism on the enlargement of renal cyst in patients with polycystic kidney disease: Genetic background of renal cyst growth
.
|
31746731 |
2020 |
|
rs5361
|
|
Episodic Kinesigenic Dyskinesia 1
|
|
0.010 |
GeneticVariation
|
BEFREE |
To determine the role of E-selectin gene S128R polymorphism on the enlargement of renal cysts in patients with polycystic kidney disease (PKD).
|
31746731 |
2020 |
|
rs5361
|
|
Polycystic Kidney Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The role of serum E-selectin level and E-selectin gene S128R polymorphism on the enlargement of renal cyst in patients with polycystic kidney disease: Genetic background of renal cyst growth
.
|
31746731 |
2020 |
|
rs5361
|
|
Renal cyst
|
|
0.010 |
GeneticVariation
|
BEFREE |
The role of serum E-selectin level and E-selectin gene S128R polymorphism on the enlargement of renal cyst in patients with polycystic kidney disease: Genetic background of renal cyst growth
.
|
31746731 |
2020 |
|
rs5361
|
|
Malignant neoplasm of ovary
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we investigated the association of PPARG Pro12Ala, IL6-174G/C, E-selectin S128R, NFKB1-94 ins/del, NFKBIA-826C/T, and ICAM-1 K469E polymorphisms with ovarian cancer risk in a Chinese population.
|
25659662 |
2016 |
|
rs5361
|
|
Carcinoma, Ovarian Epithelial
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we investigated the association of PPARG Pro12Ala, IL6-174G/C, E-selectin S128R, NFKB1-94 ins/del, NFKBIA-826C/T, and ICAM-1 K469E polymorphisms with ovarian cancer risk in a Chinese population.
|
25659662 |
2016 |
|
rs5361
|
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
It is concluded that the E-selectin S149R polymorphisms is associated with the oncogenesis of breast cancer in a population in northern Iran.
|
26828984 |
2016 |
|
rs5361
|
|
ovarian neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we investigated the association of PPARG Pro12Ala, IL6-174G/C, E-selectin S128R, NFKB1-94 ins/del, NFKBIA-826C/T, and ICAM-1 K469E polymorphisms with ovarian cancer risk in a Chinese population.
|
25659662 |
2016 |
|
rs5361
|
|
Acute Chest Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs5361 E-selectin gene polymorphism is not a susceptibility marker for ACS in Western Mexico population.
|
25147432 |
2014 |
|
rs5361
|
|
Acute Coronary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
Assessment of the E-selectin rs5361 (561A>C) polymorphism and soluble protein concentration in acute coronary syndrome: association with circulating levels.
|
25147432 |
2014 |
|
rs5361
|
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs5361 (561A>C) polymorphism in the E-selectin gene has been linked to changes in gene expression, affinity for its receptor, and plasmatic levels; therefore it is associated with an increased risk of cardiovascular disease.
|
25147432 |
2014 |
|
rs5361
|
|
Graves Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.
|
23242661 |
2013 |
|
rs5361
|
|
Recurrent aphthous ulcer
|
|
0.010 |
GeneticVariation
|
BEFREE |
This is the first report to link inheritance of the A allele, AA and AC genotypes of the E-selectin rs5361 polymorphism with increased risk of RAS.
|
23772946 |
2013 |
|
rs5361
|
|
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we explored the association between two common variants in the E-selectin gene (rs5361A/C and rs5355C/T) and EH in the Uygur, Kazakh and Han populations in the Xinjiang area.
|
22158116 |
2012 |
|
rs5361
|
|
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that the common variant rs5361 is strongly associated with EH in Han individuals and weakly associated in Uygur individuals.
|
22158116 |
2012 |
|
rs5361
|
|
Malignant neoplasm of pancreas
|
|
0.010 |
GeneticVariation
|
BEFREE |
E-selectin S128R "C" allele may confer an increased susceptibility to pancreatic cancer development, while its carriage status does not appear to be related to the aggressive features of this malignancy.
|
20607758 |
2010 |
|
rs5361
|
|
Pancreatic carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
E-selectin S128R "C" allele may confer an increased susceptibility to pancreatic cancer development, while its carriage status does not appear to be related to the aggressive features of this malignancy.
|
20607758 |
2010 |
|
rs5361
|
|
Secondary Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
We postulated that some polymorphisms within the E-selectin gene, especially the S128R polymorphism, may increase the risk of metastases by facilitating adhesion of tumour cells to the endothelium.
|
19361981 |
2009 |
|
rs5361
|
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In multivariate analysis, the S128R polymorphism was associated with shorter event-free survival (EFS) and overall survival (OS) in the whole population (EFS: P=.003, HR 1.82, 95% CI 1.23-2.70; OS: P<10(-4), HR 4.31, 95% CI 2.46-10.99), in patients with stage II CRC(EFS: P=.04, HR 1.92, 95% CI 1.02-3.60; OS: P=.02, HR 4.44, 95% CI 1.16-17.03), and in patients with stage III CRC (EFS: P=.04, HR 1.68, 95% CI 1.01-2.80; OS: P=.001, HR 4.04, 95% CI 1.73-9.46).
|
19361981 |
2009 |
|
rs5361
|
|
Acute myocardial infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genotype of the S128R polymorphism was done by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 329 angiographically proven CAD patients [n=83 acute myocardial infarction (AMI) and n= 246 AMI-free] and 331 age and sex matched control individuals (angiographically proven not to have CAD).
|
19942746 |
2009 |
|
rs5361
|
|
Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The findings of this study showed that the Ser128Arg polymorphism of E-selectin might contribute to the susceptibility of Iranian individuals to periodontitis.
|
18973547 |
2009 |
|
rs5361
|
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
E-selectin gene S128R polymorphism is associated with poor prognosis in patients with stage II or III colorectal cancer.
|
19361981 |
2009 |
|
rs5361
|
|
Asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results suggest that the Ser128Arg polymorphism of the E-selectin gene is a genetic factor that may be associated with the severity of asthma.
|
17563404 |
2007 |
|
rs5361
|
|
Malignant neoplasm of colon stage IV
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the Ser128Arg (a561c at the nucleotide level) polymorphism in the E-selectin gene in patients with metastatic colon cancer and its functional significance.
|
17372905 |
2007 |
|
rs5361
|
|
Brucellosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of the Arg/Arg genotype of the Ser128Arg polymorphism was significantly increased in brucellosis patients compared with controls (13.6% versus 6.2%, P=0.03).
|
17392035 |
2007 |