DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Rheumatoid Arthritis ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1042544

HLA-DPB1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs1042663

C2 ; CYP21A2 ; C2-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs1042663

C2 ; CYP21A2 ; C2-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs1042663

C2 ; CYP21A2 ; C2-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs1046080

PRRC2A

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs10484544

LOC105375002

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs10484560

TSBP1 ; TSBP1-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs10484566

PSMB9

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs1049281

HLA-C

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs10494360

FCGR2A

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASCAT

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.

24532676

2015

dbSNP:

rs1051336

HLA-DRA

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs10520789

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASCAT

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.

22569225

2012

dbSNP:

rs1052248

LST1 ; NCR3

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs1055569

HCP5 ; HCG26

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs1057523354

COL4A1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

CausalMutation

CLINVAR

dbSNP:

rs1059288

RGL2 ; TAPBP

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs1063355

HLA-DQB1 ; HLA-DQB1-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs1063355

HLA-DQB1 ; HLA-DQB1-AS1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs1063635

MICA

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways.

21653640

2011

dbSNP:

rs10683701

OS9

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASCAT

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.

24532676

2015

dbSNP:

rs10739537

LOC105376250

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASCAT

Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis.

30166627

2018

dbSNP:

rs1075496

NRM

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs10760126

PHF19

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASCAT

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.

24532676

2015

dbSNP:

rs1076828

DHX16

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs1076828

DHX16

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007