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rs1800629
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Virus Diseases
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0.010 |
GeneticVariation
|
BEFREE |
Inconsistency of reported associations between the tumor necrosis factor-alpha-308 (TNFα-308) polymorphism (rs1800629) and dengue virus infection prompted a meta-analysis, to obtain more precise estimates.
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28495402 |
2017 |
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rs1800629
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Aspirin exacerbated respiratory disease
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0.010 |
GeneticVariation
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BEFREE |
The GA genotype of rs1800629 is associated with genetic susceptibility to AERD, but it does not correlate to protein serum levels.
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29172674 |
2017 |
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rs1800629
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Caries (morphologic abnormality)
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0.010 |
GeneticVariation
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BEFREE |
The ENAM rs3796703 CT genotype increased caries susceptibility by 60.9% compared to the CC genotype (β=0.746, OR=1.609), and the TNF-α rs1800629 AG genotype reduced ca</span>ries susceptibility by 47.4% compared to the GG genotype (β=-0.642, OR=0.526).
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28395167 |
2017 |
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rs1800629
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Reticuloendotheliosis, X-linked
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0.010 |
GeneticVariation
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BEFREE |
In the present study, we investigated the role of a promoter region polymorphism rs1800629 (-308G>A) in the inflammatory pathway component TNF-α and its effects on the expression of TNF-α and downstream molecules tumor necrosis factor receptor 1 and 2 (TNFR1 and TNFR2), v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), and interleukin 6 (IL-6) in KC development.
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28702675 |
2017 |
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rs1800629
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melanoma
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0.010 |
GeneticVariation
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BEFREE |
We performed a meta-analysis to assess the relationship between single nucleotide polymorphisms in the TNF-α promoter region (rs1800629 and rs361525) and susceptibility to squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and melanoma.
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28881857 |
2017 |
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rs1800629
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Squamous cell carcinoma
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0.010 |
GeneticVariation
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BEFREE |
These data indicate that the AA genotype of <i>TNF-α</i> rs1800629, but not rs361525, is associated with an increased risk of SCC, suggesting it could potentially serve as a prognostic marker for predicting SCC risk.
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28881857 |
2017 |
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rs1800629
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Dental caries
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|
0.010 |
GeneticVariation
|
BEFREE |
The ENAM rs3796703 CT genotype increased caries susceptibility by 60.9% compared to the CC genotype (β=0.746, OR=1.609), and the TNF-α rs1800629 AG genotype reduced ca</span>ries susceptibility by 47.4% compared to the GG genotype (β=-0.642, OR=0.526).
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28395167 |
2017 |
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rs1800629
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Keratoconus
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0.010 |
GeneticVariation
|
BEFREE |
In the present study, we investigated the role of a promoter region polymorphism rs1800629 (-308G>A) in the inflammatory pathway component TNF-α and its effects on the expression of TNF-α and downstream molecules tumor necrosis factor receptor 1 and 2 (TNFR1 and TNFR2), v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), and interleukin 6 (IL-6) in KC development.
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28702675 |
2017 |
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rs1800629
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Pancreatic Diseases
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0.010 |
GeneticVariation
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BEFREE |
We genotyped the selected SNPs (rs16944, rs1052536, rs1059293, rs1136410, rs1143634, rs2069762, rs2236302, rs2387632, rs3212961, rs3734299, rs3803258, rs4962081, rs7234941, rs7243091, rs12957119, and rs1800629) in 344 PNET sporadic cases and 2,721 controls in the context of the PANcreatic Disease ReseArch (PANDoRA) consortium.<b>Results:</b> After correction for multiple testing, we did not observe any statistically significant association between the SNPs and PNET risk.
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28765340 |
2017 |
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rs1800629
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Polycystic Ovary Syndrome
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0.010 |
GeneticVariation
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BEFREE |
We thus found that both the genotypic and allelic distributions of rs4645843 were significantly different between PCOS and control groups (p = 0.03 and 0.024, respectively), whereas those of rs1800629 were similar between the groups.
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28993561 |
2017 |
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rs1800629
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Post-Traumatic Stress Disorder
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0.010 |
GeneticVariation
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BEFREE |
To our knowledge, this is the first time rs1800629 has been investigated in PTSD contributing to a growing body of literature that identifies the GG as a risk genotype for psychiatric disorders in Caucasian cohorts.
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28160694 |
2017 |
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rs1800629
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Abnormal behavior
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0.010 |
GeneticVariation
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BEFREE |
To our knowledge, this is the first time rs1800629 has been investigated in PTSD contributing to a growing body of literature that identifies the GG as a risk genotype for psychiatric disorders in Caucasian cohorts.
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28160694 |
2017 |
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rs1800629
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Osteoarthritis, Knee
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0.010 |
GeneticVariation
|
BEFREE |
The objective of the present study is to investigate if there is a potential association between the single-nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha gene (TNF-α -308G/A, rs1800629) and the susceptibility to and severity of early-onset knee osteoarthritis in the Egyptian female population.
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28695434 |
2017 |
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rs1800629
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Heart Failure, Diastolic
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0.010 |
GeneticVariation
|
BEFREE |
The study aimed to assess the clinical significance of selected single nucleotide polymorphisms (SNPs) in patients with diastolic heart failure (HF): inflammation [-174 G/C Interleukin -6 (IL-6) rs1800795, tumor necrosis factor (TNF)-608 G/A rs1800629], fibrosis [Arg25Pro transforming growth factor β (TGF β) rs1800471], endothelial function [-786 T/C nitric oxide synthase (NOS) rs2070744], glucose and lipid metabolism [Pro12Ala peroxisome proliferator activated receptor (PPAR)γ rs1801282], and vitamin D metabolism [cytochrome P450 27B1 (CYP27B1) C-1260A].110 patients with HF with preserved and mid-range ejection fraction (HFpEF and HFmrEF) were recruited.
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28827564 |
2017 |
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rs1800629
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Hepatitis B, Chronic
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0.010 |
GeneticVariation
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BEFREE |
To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection.
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29054398 |
2017 |
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rs1800629
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Myocardial Infarction
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0.010 |
GeneticVariation
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BEFREE |
Association between TNF-α rs1800629 polymorphism and the risk of myocardial infarction: A meta-analysis.
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27706628 |
2016 |
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rs1800629
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Impaired cognition
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0.010 |
GeneticVariation
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BEFREE |
Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients.
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27701469 |
2016 |
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rs1800629
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Type 2 lepra reaction
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0.010 |
GeneticVariation
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BEFREE |
We genotyped rs1800629 in 326 leprosy cases from Bahia State, Brazil, including 72 paucibacillary (PB) and 47 multibacillary (MB) without reactions, and 69 reversal reaction (RR) and 78 erythema nodosum leprosum (ENL) with reactions.
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26829382 |
2016 |
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rs1800629
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Diabetes
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0.010 |
GeneticVariation
|
BEFREE |
An association between the A allele of rs1800629 and type of diabetes was found.
|
26821796 |
2016 |
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rs1800629
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Adenocarcinoma Of Esophagus
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0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that TNF-α-308 G>A (rs1800629) is not significantly associated with a risk of esophageal squamous cell carcinoma and esophageal adenocarcinoma.
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27821804 |
2016 |
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rs1800629
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Erythema nodosum leprosum
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0.010 |
GeneticVariation
|
BEFREE |
We genotyped rs1800629 in 326 leprosy cases from Bahia State, Brazil, including 72 paucibacillary (PB) and 47 multibacillary (MB) without reactions, and 69 reversal reaction (RR) and 78 erythema nodosum leprosum (ENL) with reactions.
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26829382 |
2016 |
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rs1800629
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Diabetes Mellitus
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0.010 |
GeneticVariation
|
BEFREE |
An association between the A allele of rs1800629 and type of diabetes was found.
|
26821796 |
2016 |
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rs1800629
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Pemphigus
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0.010 |
GeneticVariation
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BEFREE |
Tumor necrosis factor (TNF)-α -308G/A (rs1800629) polymorphism distribution in North India and its association with pemphigus: Case-control study and meta-analysis.
|
26761187 |
2016 |
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rs1800629
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Visually threatening diabetic retinopathy
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0.010 |
GeneticVariation
|
BEFREE |
After adjustment for age, sex, diabetes duration, HbA1c, hypertension and nephropathy, no significant association was found between rs1800629 or rs361525 and sight-threatening diabetic retinopathy.
|
26821796 |
2016 |
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rs1800629
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Acute cerebral ischemia
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0.010 |
GeneticVariation
|
BEFREE |
The final multivariate model for acute cerebral ischemia risk included high white blood cell count and reticulocyte count, acute chest syndrome rate, and the single nucleotide polymorphisms (SNPs) TEK rs489347 and TNF-α rs1800629.
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27520094 |
2016 |