Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE The prognostic significance of the Arg72Pro polymorphism of the p53 tumour suppressor gene in cancer is controversial. 17400332

2007
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE Previous studies have suggested associations between variants in TP53 (R72P) and MDM2 (SNP309) and cancer risk. 17909070

2007
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE The Arg72Pro substitution did not associate with decreased risk of cancer. 17535973

2007
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer. 16721787

2006
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE To explore the impact of the p53 PIN3-Arg72Pro haplotype on colorectal adenoma formation and progression to cancer. 17374954

2006
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers. 16419081

2006
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE Statistically significant associations were noted between SNPs in beta-catenin and APOE and a positive family history of cancer (beta-catenin: p=0.034, APOE: p=0.033); tumor location and a DCC SNP (p=0.038) and the P53 R72P mutation and survival (p=0.0336). 15523694

2005
dbSNP: rs1131691014
rs1131691014
TP53
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE Codon 72 exon 4 polymorphism (Arg72Pro) of the p53 gene has been implicated in cancer risk. 15633234

2005