|
rs12980275
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
We examined the association between IL28B genotype for rs12980275 and risk of type 2 diabetes and diabetes-related complications.
|
25663241 |
2015 |
|
rs1800795
|
|
Complications of Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications.
|
25839939 |
2015 |
|
rs361525
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications.
|
25839939 |
2015 |
|
rs1801157
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications.
|
25839939 |
2015 |
|
rs1800629
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications.
|
25839939 |
2015 |
|
rs12976445
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
We identified miR-125a as a direct regulator of IL-6R, and the genotype of rs12976445 might be a novel predictor of the development of DN in DM.
|
26563755 |
2015 |
|
rs2910164
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to investigate whether the single-nucleotide polymorphism (SNP) rs2910164 residing within microRNA-146a (miR-146a) is associated with diabetic microvascular complications diabetic nephropathy (DN), proliferative diabetic retinopathy (PDR) or diabetic macular oedema (DME) in either Caucasian patients with type 1 (T1DM) or type 2 (T2DM) diabetes mellitus.
|
26997512 |
2016 |
|
rs7533564
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
A locus on chromosome 1, rs7533564 (P = 1.9 × 10(-9)), was associated with skin intrinsic fluorescence measured by SCOUT DS (excitation 375 nm, emission 435-655 nm), which remained significant after adjustment for time-weighted HbA1c (P = 1.7 × 10(-8)). rs7533564 was associated with mean HbA1c in meta-analysis (P = 0.0225), mean glycated albumin (P = 0.0029), and glyoxal hydroimidazolones (P = 0.049), an AGE measured in skin biopsy collagen, in DCCT. rs7533564 was not associated with diabetes complications in DCCT/EDIC or with SF in subjects without diabetes (nondiabetic [ND]) (N = 8,721).
|
27207532 |
2016 |
|
rs1799983
|
|
Complications of Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
The association between <i>NOS3</i> rs1799983 polymorphisms and DNA methylation suggests gene-epigenetic mechanisms through which vascular diabetes complications develop despite adequate metabolic control.
|
27990443 |
2016 |
|
rs769985775
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study presents nine patients with mitochondrial tRNA Leu (UUR) m.3243A>G mutation and compares the clinical characteristics and diabetes complications with type 1 diabetes (T1DM) or early onset type 2 diabetes (T2DM).
|
28599824 |
2017 |
|
rs713041
|
|
Complications of Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Thus, the association of a functional variant in the gene encoding glutathione peroxidase 4 (rs713041) with this diabetic complication was investigated in 341 individuals with type 1 diabetes evaluated for cardiac autonomic neuropathy status (61.7% women, 34 [27-42] years old; diabetes duration: 21 [15-27] years; HbA1c: 8.3% [7.4-9.4]; as median [interquartile interval]).
|
30599773 |
2019 |
|
rs1800624
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs1800624 SNP involves <i>AGER</i> gene regulation and may be related to reduced risk of heart disease, cancer, Crohn's disease, and type 1 diabetes complications.
|
30863465 |
2019 |
|
rs713041
|
|
Complications of Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Given the participation of oxidative stress in the pathogenesis of diabetic complications, we evaluated, in type 1 diabetes (T1D) individuals, the association between diabetic retinopathy (DR) and functional single nucleotide polymorphisms (SNPs) in regulatory regions of two genes belonging to the antioxidant glutathione (GSH) system: rs17883901 in GCLC and rs713041 in GPX4.
|
30959073 |
2019 |
|
rs17883901
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Given the participation of oxidative stress in the pathogenesis of diabetic complications, we evaluated, in type 1 diabetes (T1D) individuals, the association between diabetic retinopathy (DR) and functional single nucleotide polymorphisms (SNPs) in regulatory regions of two genes belonging to the antioxidant glutathione (GSH) system: rs17883901 in GCLC and rs713041 in GPX4.
|
30959073 |
2019 |