|
rs1800795
|
|
Graft-vs-Host Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Furthermore, the IL-6R rs4845618 donor genotype showed an association with severe acute graft-versus-host disease (GVHD), whereas the donor genotype of the IL-6 SNP rs1800795 was associated with decreased survival 100 days post-transplant.
|
29513361 |
2018 |
|
rs1800795
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
GG genotypes of rs1800795 in IL-6 was also associated with occurrence of tuberculosis in our patients with TA.
|
28438554 |
2018 |
|
rs1800795
|
|
Adult Liver Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subgroup analyses of rs1800797 also suggested non-significant association and rs1800795 played a protective role in liver cancer.
|
29842912 |
2018 |
|
rs1800795
|
|
Non-alcoholic Fatty Liver Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study was conducted to investigate the association of CRP rs1130864 (1444C/T), IL-6 rs1800795 (-174G/C) and LEPR rs1137101 (Q223R) genes with OSA and NAFLD in Asian Indians residing in North India.
|
30001365 |
2018 |
|
rs1800795
|
|
Congenital arteriovenous malformation
|
|
0.010 |
GeneticVariation
|
BEFREE |
We genotyped 11 candidate variants: four variants reported as associated with lung AVM in HHT (PTPN14 rs2936018, USH2A rs700024, ADAM17 rs12474540, rs10495565), and seven variants reported as associated with sporadic BAVM or ICH (APOE ε2, ANGPTL4 rs11672433, EPHB4 rs314308, IL6 rs1800795, IL1B rs1143627, ITGB8 rs10486391, TNFA rs361525).
|
29932521 |
2018 |
|
rs1800795
|
|
Sleep Apnea, Obstructive
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study was conducted to investigate the association of CRP rs1130864 (1444C/T), IL-6 rs1800795 (-174G/C) and LEPR rs1137101 (Q223R) genes with OSA and NAFLD in Asian Indians residing in North India.
|
30001365 |
2018 |
|
rs1800795
|
|
Childhood Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subgroup analysis indicated that rs1800795 was significantly associated with increased risk of cervical cancer, colorectal cancer, breast cancer, prostate cancer, lung cancer, glioma, non-Hodgkin's lymphoma and Hodgkin's lymphoma but not gastric cancer and multiple myeloma.
|
29552316 |
2018 |
|
rs1800795
|
|
Polycystic Ovary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results suggested that the IL-6 rs1800795</span> polymorphism is a protective factor for PCOS susceptibility.
|
30024552 |
2018 |
|
rs1800795
|
|
Atrial Fibrillation
|
|
0.010 |
GeneticVariation
|
BEFREE |
Polymorphisms in PITX2 (rs2200733) and IL6 (rs1800795) are associated with postoperative atrial fibrillation in adults but have not been studied in CHD.
|
29800783 |
2018 |
|
rs1800795
|
|
Diabetic foot ulcer
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU).
|
30009916 |
2018 |
|
rs1800795
|
|
Anthracosilicosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Associations of polymorphisms in the cytokine genes IL1β (rs16944), IL6 (rs1800795), IL12b (rs3212227) and growth factor VEGFA (rs2010963) with anthracosilicosis in coal miners in Russia and related genotoxic effects.
|
29378067 |
2018 |
|
rs1800795
|
|
Mental disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the present study, we genotyped two interleukin 6 (IL-6) variants (rs2069845 and rs1800795) in 320 suicide attempters, 236 suicide completers, and 341 individuals without any history of psychiatric disorders or suicide ideation.
|
30269203 |
2018 |
|
rs1800795
|
|
Malignant neoplasm of liver
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subgroup analyses of rs1800797 also suggested non-significant association and rs1800795 played a protective role in liver cancer.
|
29842912 |
2018 |
|
rs1800795
|
|
Abnormal behavior
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the present study, we genotyped two interleukin 6 (IL-6) variants (rs2069845 and rs1800795) in 320 suicide attempters, 236 suicide completers, and 341 individuals without any history of psychiatric disorders or suicide ideation.
|
30269203 |
2018 |
|
rs1800795
|
|
Neoplasm Metastasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings suggest that GG SNP at IL-6: rs1800795 may indicate an increased risk of metastasis of primary breast cancer.
|
28732081 |
2017 |
|
rs1800795
|
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
In view of this, the current study aimed to investigate the possible association of 5' promoter polymorphisms G-597A (rs1800797), G-572C (rs1800796) and G-174C (rs1800795) with the risk of SLE.
|
28530463 |
2017 |
|
rs1800795
|
|
Premature coronary artery atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The risk allele frequencies (RAFs) of rs1800795 <i>(IL6)</i> and rs187238 <i>(IL18)</i> cytokine gene promoter SNPs were significantly higher in the PCAD cases as compared with the controls.
|
27559091 |
2017 |
|
rs1800795
|
|
Childhood asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In recent years, cytokines and their receptors have been shown to be highly polymorphic, and this prompted us to investigate interleukin 6 promoter polymorphisms at position -174G/C (rs1800795) and at -572G/C (rs1800796) in relation to asthma in children.
|
28185773 |
2017 |
|
rs1800795
|
|
Secondary Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
The initial study suggested that GG relative to CG at rs1800795 (OR 1.52; 95% CI 1.14-2.02; p = 0.004) was significantly associated with the development of metastases.
|
28732081 |
2017 |
|
rs1800795
|
|
Graves Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Together, our data support that rs1800795 within the <i>IL</i>-6 gene confers genetic susceptibility for GD.
|
29228744 |
2017 |
|
rs1800795
|
|
PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL-6 genotypes of rs1800795 GC and rs1800796 GG might point to a relatively high risk for T2D patients suffering from PDR in a Chinese population and they were associated with elevation of IL-6 expression in both mRNA and protein.
|
28651253 |
2017 |
|
rs1800795
|
|
Heart Failure, Diastolic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study aimed to assess the clinical significance of selected single nucleotide polymorphisms (SNPs) in patients with diastolic heart failure (HF): inflammation [-174 G/C Interleukin -6 (IL-6) rs1800795, tumor necrosis factor (TNF)-608 G/A rs1800629], fibrosis [Arg25Pro transforming growth factor β (TGF β) rs1800471], endothelial function [-786 T/C nitric oxide synthase (NOS) rs2070744], glucose and lipid metabolism [Pro12Ala peroxisome proliferator activated receptor (PPAR)γ rs1801282], and vitamin D metabolism [cytochrome P450 27B1 (CYP27B1) C-1260A].110 patients with HF with preserved and mid-range ejection fraction (HFpEF and HFmrEF) were recruited.
|
28827564 |
2017 |
|
rs1800795
|
|
Rheumatic Heart Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We examined the associations of 8 selected polymorphisms in seven inflammatory genes: IL-6 [rs1800795G/C], IL-10 [rs1800896G/A], TNF-A [rs1800629G/A], IL-1β [rs2853550C/T], IL-1VNTR [rs2234663], TGF-β1 [rs1800469C/T]; [rs1982073T/C], and CTLA-4 [rs5742909C/T] with RHD risk.
|
27118427 |
2016 |
|
rs1800795
|
|
Dyslipidemias
|
|
0.010 |
GeneticVariation
|
BEFREE |
To assess the role of Helicobacter pylori infection and interleukin 6 polymorphism -174 (rs1800795) in dyslipidemia.
|
26781506 |
2016 |
|
rs1800795
|
|
Cerebrovascular accident
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study investigated the frequency of interleukin-6 (IL-6) promoter polymorphism rs1800795 (-174 G>C), possible association of this polymorphism with IL-6 levels and the outcome after stroke in 95 patients with acute ischemic stroke and 268 healthy subjects.
|
27049557 |
2016 |