Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
C 1.000 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
C 1.000 GeneticVariation GWASDB Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Our study suggested that the C allele of rs13266634 was associated with higher odds of T2D, and higher plasma zinc was associated with lower odds. 24306209

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Thus, the present study aimed to investigate the association between rs13266634 polymorphism and T2DM in Fars province, Southern Iran and compare the results with other populations. 24449369

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE The variant rs13266634 in SLC30A8, encoding a β-cell-specific zinc transporter, is associated with type 2 diabetes. 24471563

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Through sequencing or genotyping of ~150,000 individuals across 5 ancestry groups, we identified 12 rare protein-truncating variants in SLC30A8, which encodes an islet zinc transporter (ZnT8) and harbors a common variant (p.Trp325Arg) associated with T2D risk and glucose and proinsulin levels. 24584071

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Gene-environment interaction analysis showed a significant interaction between rs13266634 in SLC30A8 gene and age on T2DM risk (P<0.0001). 24736664

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05]. 24993573

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We observed an association between allele variants of SLC30A8 [rs13266634 (C/T)] and type 2-diabetes (P = 0.04). 25501231

2014

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Nine variants in FTO rs8050136, WFS1 rs10010131, CDKN2A/B rs10811661, KCNJ11 rs5219, CDC123/CAMK1D rs12779790, JAZF1 rs864745, SLC30A8 rs13266634, CDKAL1 rs10946398, and HHEX/IDE rs5015480 were significantly associated with T2DM (P < 0.05). 23298195

2013

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We hypothesize that impaired function driven by rs13266634 increases T2D risk when combined with serum levels of nutrients. 23334806

2013

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Meanwhile PPARG-2 Pro12Ala, CDKN2A/2B rs10811661, IGF2BP2 rs4402960, HHEX rs7923837, CDKAL1 rs7754840, EXT2 rs1113132 and SLC30A8 rs13266634 were found to have no significant association with T2D among Arabs. 23458876

2013

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160

2012

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE A case-control study was performed in Han Chinese subjects with normal control (n=152) and T2DM (n=227), we genotyped rs7903146 and rs11196218 at TCF7L2, rs13266634 at SLC30A8, rs3811951 at PCSK1 and rs2021785 at PCSK2. 21437630

2012

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of TaqMan assays in 235 kidney transplant patients medicated with tacrolimus: rs4402960 and rs1470579 in IGF2BP2; rs1111875 in HHEX; rs10811661 upstream of CDKN2A/B; rs13266634 in SLC30A8; rs1801282 in PPARG; rs5215 in KCNJ11. 22569928

2012

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE For this reason, the present study looked at the contribution of ENNP1 (rs1044498), IGF2BP2 (rs1470579), KCNJ11 (rs5219), MLXIPL (rs7800944), PPARγ (rs1801282), SLC30A8 (rs13266634) and TCF7L2 (rs7903146) SNPs to the risk of T2DM in Lebanese and Tunisian Arabs. 22749234

2012

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). 22923468

2012

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 21874001

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Our present meta-analysis provided evidence that SLC30A8 (rs13266634) C allele carriers could elevate the risk of type 2 diabetes, especially in Europeans and Asians. 20167458

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE We hypothesised that the correlation between autoantibody specificity for the ZnT8 Arg325Trp isoforms and the type 2 diabetes-associated rs13266634 may affect β-cell function at type 1 diabetes (T1D) onset. 20836749

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Recent genome wide association studies indicated that Arg325Trp polymorphism of Slc30a8 encoding ZnT8 is associated with susceptibility to type 2 diabetes. 21099260

2011

dbSNP: rs13266634
rs13266634
Diabetes Mellitus, Non-Insulin-Dependent
1.000 GeneticVariation BEFREE Our meta-analysis results revealed the significant association between rs13266634 C/T polymorphism and T2DM and IGT, but did not support the association between this polymorphism and T1DM. 21131091

2011