rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
TLR1 rs4833095 SNP was associated with an increased risk of GC in a European population, while PRKAA1 rs13361707 genetic variant was not linked with GC.
|
30574617 |
2018 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
The meta-analysis reveals that the PRKAA1 rs13361707 T>C polymorphism has a significant relationship with increased GC risk.
|
29620653 |
2018 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
In similar, an increased risk of gastric cancer was also observed for rs13361707</span> TC genotype (adjusted OR = 1.47, 95%CI: 1.01-2.14, p = 0.043; additive model: adjusted OR = 1.22, 95%CI: 1.02-1.47, p = 0.033).
|
30253744 |
2018 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
Correlation between protein kinase catalytic subunit alpha-1 gene rs13361707 polymorphism and gastric cancer susceptibility in asian populations.
|
28978122 |
2017 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
In summary, these results indicated that the C allele of PRKAA1 rs13361707 was a low-penetrate risk factor for GCa.
|
26485766 |
2015 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
In the dominant model, SNPs rs13361707 [odds ratio (OR) = 1.51, 95%CI: 1.07-2.11)], rs154268 (OR = 1.65, 95%CI: 1.22-2.22), rs6882903 (OR = 1.48, 95%CI: 1.09-2.00), and rs10074991 (OR = 1.53, 95%CI: 1.09-2.16) were significantly associated with an increased risk of gastric cancer.
|
25024613 |
2014 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
Our study showed that the rs13361707 polymorphism was associated with increased risk of gastric cancer in a Korean population.
|
23861218 |
2013 |
rs13361707
|
|
Malignant neoplasm of stomach
|
|
0.780 |
GeneticVariation
|
BEFREE |
These findings indicate that the three SNPs (rs4072037, rs13361707 and rs2274223) identified in the GWASs may interact with H. pylori infection to increase the risk of GC.
|
24069371 |
2013 |
rs9841504
|
|
Malignant neoplasm of stomach
|
|
0.720 |
GeneticVariation
|
BEFREE |
Those subjects with both the risk alleles MUC1 rs9841504 and ZBTB20 rs4072037 had a greater than 3-fold increased risk of gastric cancer.
|
27127881 |
2016 |
rs9841504
|
|
Malignant neoplasm of stomach
|
|
0.720 |
GeneticVariation
|
BEFREE |
However, we found no association between rs9841504 and gastric cancer risk.
|
23861218 |
2013 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the case-control study, rs1042522 (<i>TP53</i>) was associated with a stronger risk for developing gastric cancer in the sample stratified for diffuse subtype patients when compared to the risk observed for the total cases; CTC haplotype (rs699947/rs833061/rs2010963 <i>VEGFA</i>) was associated with risk while rs699947 was associated with protection for gastric malignancy in the total sample.
|
30551681 |
2018 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found that the polymorphisms of P53 (rs1042522) and MDM2 (rs2279744) are associated with gastric cancer risk, whereas no significant association was observed between variant genotype of other two polymorphisms (MDM4 rs1380576 and Hausp rs1529916) and gastric cancer risk.
|
25479941 |
2015 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
The purpose of this study was to examine the role of the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms in the susceptibility of gastric cancer.
|
25658980 |
2015 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that TP53 rs1042522 polymorphism might contribute to the susceptibility of gastric cancer under the dominant model, especially in Eastern Asians.
|
24534481 |
2014 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC.
|
25227851 |
2014 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
The purpose of the present hospital-based case-control study was to investigate the association between the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of gastric cancer.
|
25190020 |
2014 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of gastric cancer in Asians.
|
22780299 |
2012 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Overall, a significant association was detected between the p53 Arg72Pro polymorphism and GC risk (Pro-allele vs. Arg-allele: OR=1.05, 95%CI=1.01-1.08; Pro/Pro vs. Arg/Arg: OR=1.13, 95%CI=1.04-1.22).
|
22901123 |
2012 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians.
|
22631671 |
2012 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that Pro allele in P53 Arg72Pro is significantly associated with the increased risks of digestive tract cancers, especially for Asians, and for gastric cancer, colorectal cancer and gallbladder and pancreatic cancer.
|
21376265 |
2011 |
rs1042522
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Aiming to evaluate the associations between host cell proliferation-related genetic polymorphisms and gastric cancer susceptibility, we reviewed the related studies published until 15 September 2008 and quantitatively summarized the associations of the most widely studied polymorphisms (TP53 Arg72Pro, L-myc EcoRI) using meta-analysis.
|
19536170 |
2009 |
rs1052133
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed there was no association between hOGG1 rs1052133 and GC.
|
28415729 |
2017 |
rs1052133
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis.
|
26600527 |
2015 |
rs1052133
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to gastric cancer.
|
22799296 |
2012 |
rs1052133
|
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our result could explain the association between hOGG1 Ser326Cys polymorphism and GC risk.
|
22294108 |
2012 |