Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12521868
rs12521868
IRF1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.810 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs2188962
rs2188962
IRF1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.810 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs2188962
rs2188962
IRF1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.810 GeneticVariation GWASCAT Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. 20570966

2010
dbSNP: rs2188962
rs2188962
IRF1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.810 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs11242111
rs11242111
IRF1-AS1 ; LINC02863
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		A 0.800 GeneticVariation GWASCAT Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. 23969696

2013
dbSNP: rs2070729
rs2070729
IRF1 ; IRF1-AS1
CUI: C0032181
Disease: Platelet Count measurement
Platelet Count measurement 		A 0.800 GeneticVariation GWASCAT New gene functions in megakaryopoiesis and platelet formation. 22139419

2011
dbSNP: rs2106854
rs2106854
IRF1-AS1
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		T 0.800 GeneticVariation GWASCAT Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. 23969696

2013
dbSNP: rs2188962
rs2188962
IRF1-AS1
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs2188962
rs2188962
IRF1-AS1
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		T 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233

2012
dbSNP: rs2522056
rs2522056
IRF1-AS1
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		A 0.800 GeneticVariation GWASCAT Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. 20031576

2009
dbSNP: rs1004234
rs1004234
IRF1-AS1 ; LINC02863
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs1004234
rs1004234
IRF1-AS1 ; LINC02863
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs1004234
rs1004234
IRF1-AS1 ; LINC02863
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs1004234
rs1004234
IRF1-AS1 ; LINC02863
CUI: C0008313
Disease: Cholangitis, Sclerosing
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs1004234
rs1004234
IRF1-AS1 ; LINC02863
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs10076733
rs10076733
IRF1-AS1 ; LINC02863
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.700 GeneticVariation GWASCAT Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. 30804561

2019
dbSNP: rs1012793
rs1012793
IRF1-AS1
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		0.700 GeneticVariation GWASCAT Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. 28107422

2017
dbSNP: rs1023518
rs1023518
IRF1-AS1
CUI: C0004096
Disease: Asthma
Asthma 		T 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019
dbSNP: rs10900807
rs10900807
IRF1-AS1 ; LINC02863
CUI: C0523677
Disease: Glycine measurement
Glycine measurement 		G 0.700 GeneticVariation GWASCAT Assessing the causal association of glycine with risk of cardio-metabolic diseases. 30837465

2019
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C4310768
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C4014795
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11741255
rs11741255
IRF1-AS1
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015