Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1524107
rs1524107
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium
0.010 GeneticVariation BEFREE We observed a significant increase in risk of endometrial cancer of rs1524107 (IL6) (T/C, OR = 1.61, 95% CI = 1.09-2.37, p = 1.55 × 10<sup>-2</sup> ), rs2066992 (IL 6) (OR = 3.09, 95% CI = 2.11-4.53, p = 3.13 × 10<sup>-9</sup> ). 30828987

2019

dbSNP: rs1524107
rs1524107
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.010 GeneticVariation BEFREE We observed a significant increase in risk of endometrial cancer of rs1524107 (IL6) (T/C, OR = 1.61, 95% CI = 1.09-2.37, p = 1.55 × 10<sup>-2</sup> ), rs2066992 (IL 6) (OR = 3.09, 95% CI = 2.11-4.53, p = 3.13 × 10<sup>-9</sup> ). 30828987

2019

dbSNP: rs1524107
rs1524107
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.010 GeneticVariation BEFREE In summary, four variations (rs1800796, rs1524107, rs2069840, rs2243250) of the selected candidate SNPs were associated with susceptibility to LDD in our study. 29179499

2017

dbSNP: rs1524107
rs1524107
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE IL-6 gene polymorphisms rs1800796 and rs1524107 may serve as predictors of progression of nephropathy in Chinese patients with type 2 diabetes. 27500547

2016

dbSNP: rs1524107
rs1524107
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.010 GeneticVariation BEFREE IL-6 gene polymorphisms rs1800796 and rs1524107 may serve as predictors of progression of nephropathy in Chinese patients with type 2 diabetes. 27500547

2016

dbSNP: rs1524107
rs1524107
CUI: C1857276
Disease: Trichohepatoenteric Syndrome
Trichohepatoenteric Syndrome
0.010 GeneticVariation BEFREE We examined the role of the IL-6 (rs1524107-C/T) and IL-6 receptor (IL-6R, rs8192284-A/C, Asp358Ala) SNPs in modulating IL-6 levels and the syndrome. 20186139

2010