rs747126003
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|
Obesity
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0.020 |
GeneticVariation
|
BEFREE |
Polymorphisms in the adipokine genes, LEP, LEPR, and RETN were not associated with obesity susceptibility, whereas ADIPOQ G276T (T vs. G: odds ratio (OR), 1.59; 95% confidence interval (CI), 1.39-1.81), IL-1β C3953T (CC vs. CT+TT: OR, 1.61; 95% CI, 1.18-2.20), and TNF-α G308A (GG vs. GA+AA: OR, 1.19; 95% CI, 1.02-1.39) polymorphisms were associated with an increased risk of obesity.
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21660081 |
2012 |
rs747126003
|
|
Obesity
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|
0.020 |
GeneticVariation
|
BEFREE |
We found a relation between G174C polymorphism in IL-6 gene and G308A in TNF-alpha gene with the occurrence of obesity.
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20156727 |
2009 |
rs747126003
|
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Coronary Arteriosclerosis
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|
0.010 |
GeneticVariation
|
BEFREE |
Gene polymorphism associated with TNF-α (G308A) IL-6 (C174G) and susceptibility to coronary atherosclerotic heart disease: A meta-analysis.
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30633155 |
2019 |
rs747126003
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|
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
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|
0.010 |
GeneticVariation
|
BEFREE |
The aim of our study was to investigate the impact of interleukin (IL)-6 190C/T, IL-6 174G/C, IL-6 572G/C, tumor necrosis factor-alpha (TNF-α) 308G/A, and angiotensin-converting enzyme (ACE) I/D gene polymorphisms on Helicobacter pylori (H. pylori) infection in children.A cross-sectional study was performed on 126 children (57 children with H. pylori infection and 69 children without H. pylori infection) aged between 3 and 18 years presenting to a Pediatrics Tertiary Hospital from Romania.
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28746216 |
2017 |
rs747126003
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|
Idiopathic Nephrotic Syndrome
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|
0.010 |
GeneticVariation
|
BEFREE |
IL-6-G174C and TNFα-G308A polymorphisms may affect susceptibility to idiopathic nephrotic syndrome and might affect steroid response in INS patients.
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29190601 |
2017 |
rs747126003
|
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Childhood Osteosarcoma
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|
0.010 |
GeneticVariation
|
BEFREE |
Our subgroup analysis showed a significant association between IL-6 174G/C and IL-10 1082A/G and OS risk in Asians, while no such significant correlation was observed with TNF-α 308G/A, TNF-α 238G/A, TNF-β 252A/G and TGF-β1 29T/C polymorphisms.
|
29228633 |
2017 |
rs747126003
|
|
Nephrotic Syndrome, Minimal Change
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|
0.010 |
GeneticVariation
|
BEFREE |
IL-6-G174C and TNFα-G308A polymorphisms may affect susceptibility to idiopathic nephrotic syndrome and might affect steroid response in INS patients.
|
29190601 |
2017 |
rs747126003
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Osteosarcoma
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|
0.010 |
GeneticVariation
|
BEFREE |
Our subgroup analysis showed a significant association between IL-6 174G/C and IL-10 1082A/G and OS risk in Asians, while no such significant correlation was observed with TNF-α 308G/A, TNF-α 238G/A, TNF-β 252A/G and TGF-β1 29T/C polymorphisms.
|
29228633 |
2017 |
rs747126003
|
|
Osteosarcoma of bone
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|
0.010 |
GeneticVariation
|
BEFREE |
Our subgroup analysis showed a significant association between IL-6 174G/C and IL-10 1082A/G and OS risk in Asians, while no such significant correlation was observed with TNF-α 308G/A, TNF-α 238G/A, TNF-β 252A/G and TGF-β1 29T/C polymorphisms.
|
29228633 |
2017 |
rs747126003
|
|
Infection in children
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|
0.010 |
GeneticVariation
|
BEFREE |
The aim of our study was to investigate the impact of interleukin (IL)-6 190C/T, IL-6 174G/C, IL-6 572G/C, tumor necrosis factor-alpha (TNF-α) 308G/A, and angiotensin-converting enzyme (ACE) I/D gene polymorphisms on Helicobacter pylori (H. pylori) infection in children.A cross-sectional study was performed on 126 children (57 children with H. pylori infection and 69 children without H. pylori infection) aged between 3 and 18 years presenting to a Pediatrics Tertiary Hospital from Romania.
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28746216 |
2017 |
rs747126003
|
|
Infantile nystagmus syndrome
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|
0.010 |
GeneticVariation
|
BEFREE |
IL-6-G174C and TNFα-G308A polymorphisms may affect susceptibility to idiopathic nephrotic syndrome and might affect steroid response in INS patients.
|
29190601 |
2017 |
rs747126003
|
|
Carcinoma of lung
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|
0.010 |
GeneticVariation
|
BEFREE |
TNF-α 308G/A, IL-6 174G/C, IL-1β 31T/C, IL-1β 511C/T, COX-2 8473T/C polymorphisms were not detected to be related to the risk for LC.
|
22160576 |
2012 |
rs747126003
|
|
Malignant neoplasm of lung
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|
0.010 |
GeneticVariation
|
BEFREE |
TNF-α 308G/A, IL-6 174G/C, IL-1β 31T/C, IL-1β 511C/T, COX-2 8473T/C polymorphisms were not detected to be related to the risk for LC.
|
22160576 |
2012 |
rs747126003
|
|
Primary malignant neoplasm of lung
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|
0.010 |
GeneticVariation
|
BEFREE |
TNF-α 308G/A, IL-6 174G/C, IL-1β 31T/C, IL-1β 511C/T, COX-2 8473T/C polymorphisms were not detected to be related to the risk for LC.
|
22160576 |
2012 |
rs747126003
|
|
Head and Neck Carcinoma
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|
0.010 |
GeneticVariation
|
BEFREE |
The G308A polymorphism of the TNF-alpha gene did not affect levels of inflammatory markers in patients after surgery for head and neck cancer who were treated with early enteral nutrition.
|
17560079 |
2007 |
rs747126003
|
|
Malignant Head and Neck Neoplasm
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|
0.010 |
GeneticVariation
|
BEFREE |
The G308A polymorphism of the TNF-alpha gene did not affect levels of inflammatory markers in patients after surgery for head and neck cancer who were treated with early enteral nutrition.
|
17560079 |
2007 |
rs747126003
|
|
Severe Sepsis
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|
0.010 |
GeneticVariation
|
BEFREE |
TNF-alpha 308 G/A, PAI-1 4G/4G, and EPCR mutations influence the risk of severe sepsis in children.
|
16444434 |
2006 |
rs747126003
|
|
Sepsis
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|
0.010 |
GeneticVariation
|
BEFREE |
In this study, the relationship between the TNF-alpha 308G/A, the IL-6-174 G/C, the PAI-1, the FVL, the EPCR, and the Cathepsin G (Ars 125 Ser) polymorphisms and the development and outcome of sepsis in pediatric patients was studied.
|
16444434 |
2006 |
rs747126003
|
|
Septicemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, the relationship between the TNF-alpha 308G/A, the IL-6-174 G/C, the PAI-1, the FVL, the EPCR, and the Cathepsin G (Ars 125 Ser) polymorphisms and the development and outcome of sepsis in pediatric patients was studied.
|
16444434 |
2006 |