Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE The aim of this study was to examine whether the variants of some candidate genes involved in the development of AD, namely BIN1 (rs744373), CLU (rs11136000), CR1 (rs3818361), and PICALM (rs3851179), are related to several disorders of glucose metabolism-gestational diabetes (GDM), T2DM and impaired glucose tolerance (IGT). 28316001

2017

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE In summary, this is the first study to show significan</span></span>t association between rs3818361 polymorphism and AD in Chinese population by a meta-analysis method. 26189835

2016

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE Our prevalent case study comparing prevalent AD cases (n = 428) with participants with no cognitive impairment (n = 524) revealed a significant association of rs6656401 and rs3818361 (CR1), rs2075650 (TOMM40), rs7561528 (BIN1), and rs3865444 (CD33) with late-onset AD that were robust to adjustment with age and apolipoprotein E ε4 genotype. 24176626

2014

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE We also independently replicate our observation of lower brain amyloid burden in risk allele carriers of rs3818361 in the Alzheimer's Disease Neuroimaging Initiative sample. 23022416

2013

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. 22244847

2012

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation GWASDB Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. 21460840

2011

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation GWASDB Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 21460841

2011

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation GWASCAT Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. 21460840

2011

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE Meta-analysis of available studies (n = 31,771 individuals), including previous studies and public genome-wide association study resources (Alzheimer's Disease Neuroimaging Initiative, Translational Genomics Research Institute, and Multi-site Collaborative Study for Genotype-Phenotype Associations in Alzheimer's Disease), strongly supports the effect of rs3818361 (odds ratio = 1.180, 95% confidence interval: 1.113-1.252, P < 2.99E-8) and suggests the existence of between-study heterogeneity (P < .05). 21784344

2011

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE Unadjusted, CLU (odds ratio [OR], 0.91; 95% confidence interval [CI], 0.85-0.96 for single-nucleotide polymorphism [SNP] rs11136000), CR1 (OR, 1.14; 95% CI, 1.07-1.22; SNP rs3818361), and PICALM (OR, 0.89; 95% CI, 0.84-0.94, SNP rs3851179) were associated with AD in white individuals. 20697030

2010

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation BEFREE The results revealed that there were significant differences in genotype (P=0.02) and allele (P=0.007) frequencies of the SNP rs6656401 but no in rs3818361 between AD patients and controls. 20558149

2010

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
A 0.880 GeneticVariation GWASCAT Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. 19734903

2009

dbSNP: rs3818361
rs3818361
CR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.880 GeneticVariation GWASDB Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. 19734903

2009