Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE Our data indicated that TNFAIP3 gene rs10499194, rs13207033 polymorphisms were associated with the decreased risk of RA. 27779104

2016

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE This study showed that carriers of the rs2230926 TG genotype or rs10499194 CT genotype had an increased risk for RA compared with those carrying the wild genotype (rs2230926: OR = 1.48, 95% CI = 1.17-1.86, p = 0.001; rs10499194: OR = 2.00, 95% CI = 1.46-2.74, p < 0.001). 24884566

2014

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE Childhood-onset RA was associated with TNFAIP3 rs10499194 (OR 0.60 [95% confidence interval 0.44-0.83]), PTPN22 rs2476601 (OR 1.61 [95% confidence interval 1.11-2.31]), and STAT4 rs7574865 (OR 1.41 [95% confidence interval 1.06-1.87]) variants. 23450725

2013

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE This meta-analysis confirms that the TNFAIP3 polymorphisms are associated with RA susceptibility in different ethnic groups, namely, in Europeans for rs6920220 and in Asians for rs10499194. 22402800

2012

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE The intergenic SNP rs10499194 was also associated with SLE and RA, while the risk allele for RA in Caucasians was protective against the diseases in our population. 20112363

2010

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE The next most strongly associated SNP was rs13207033 [P = 0.0001, OR (95% CI) 0.86 (0.8-0.93)] which was perfectly correlated with rs10499194, a SNP previously associated with RA in a US/European series. 19417005

2009

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE However, we were able to replicate the association signals between RA and HLA-DRB1 alleles, STAT4 (rs7574865), PTPN22 (rs2476601) and OLIG3/TNFAIP3 (rs10499194 and rs6920220). 19445664

2009

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.880 GeneticVariation BEFREE In a concurrent study, the Wellcome Trust Case Control Consortium (WTCCC) has reported strong association of rheumatoid arthritis susceptibility to a different SNP located 3.8 kb from rs10499194 (rs6920220; P = 5 x 10(-6) in WTCCC). 17982456

2007

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
C 0.880 GeneticVariation GWASDB Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. 17982456

2007

dbSNP: rs10499194
rs10499194
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
C 0.880 GeneticVariation GWASCAT Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. 17982456

2007