Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE In conclusion, some variants associated with CRC risk (rs10505477, rs6983267, rs10795668 and rs11255841) are also involved in the susceptibility to CRA and specific subtypes. 30194776

2019

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE In particular, both homozygous TT and heterozygous CT genotypes of rs10505477, as well as the GG and TG genotypes of rs6983267, were associated with risk of colorectal cancer.Our study provides summary evidence that common variants in the 8q24 are associated with risk of colorectal cancer in this large-scale research synopsis and meta-analysis. 30170403

2018

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.890 GeneticVariation GWASCAT Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. 28960316

2018

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.890 GeneticVariation GWASCAT Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. 26965516

2016

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE Long non-coding RNA (lncRNA) CASC8 rs10505477 polymorphism has been identified to be related to risk of many kinds of cancers, such as colorectal cancer, gastric cancer, and invasive ovarian cancer, and it may be involved in the prognosis of gastric cancer patients who have received platinum-based chemotherapy after surgical treatment. 27249003

2016

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE Genome-wide association studies have identified the SNP rs10505477 and SNP rs1562430 in CASC8 were associated with risk of the colorectal cancer (CRC) and breast cancer, respectively. 25302443

2015

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE Furthermore, the A allele of rs7014346, the A allele of rs10505477, and the T allele of rs4939827 were significantly related with an elevated risk of CRC only among Caucasian.Our study suggested that for CASC8 gene, SNP of rs7837328 and rs6983267 are risk factors for CRC among both Caucasian and Asian whereas rs7014346 and rs10505477 are risky gene polymorphisms only among Caucasian. 26579801

2015

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
T 0.890 GeneticVariation GWASCAT Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. 24737748

2014

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.890 GeneticVariation GWASDB Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. 24836286

2014

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
T 0.890 GeneticVariation GWASDB Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. 24737748

2014

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE Results of this study suggests that the rs6983267 and rs10505477 polymorphisms alone may not be relevant to CRC risk, but their GG haplotype plays a notable role in age at diagnosis of CRC in the Iranian population. 24528058

2014

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation GWASDB Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. 23266556

2013

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE A meta-analysis of included studies of rs10505477 polymorphisms identified allelic and genotypic associations with CRC risk in the US patients. 21722176

2011

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE Among 1,861 incident cases and 1,937 population-based controls matched on age, gender, ethnicity, and clinic, rs10505477 was associated with risk of CRC in a dominant model, with an odds ratio = 1.23, 95% confidence interval = 1.05-1.43, (p = 0.008). 17630503

2007

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.890 GeneticVariation GWASCAT Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. 17618283

2007

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation GWASDB A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. 17618284

2007

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.890 GeneticVariation BEFREE In the population-based series, we also detected statistically significant associations between two SNPs on 8q24, rs10505477 and rs6983267, and risk of CRC (P = 0.005 and P = 0.002, respectively). 18056436

2007

dbSNP: rs10505477
rs10505477
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.890 GeneticVariation GWASDB Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. 17618283

2007