Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.830 GeneticVariation GWASCAT Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. 30529582

2019

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation BEFREE Individual SNPs only had non-significant associations with CRC occurrence with HRs lower than 2, although male carriers of allele A at rs1321311 (6p21.31) may have increased risk of CRC (HR = 2.1, 95% CI 1.2-3.0). 29147930

2018

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation BEFREE Among the 22 SNPs, two (rs1321311G>T in CDKN1A and rs10411210C>T in RHPN2) were significantly associated with the survival outcomes of CRC in a multivariate survival analysis. 25799222

2015

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation BEFREE The present results suggest that the genetic variants of the CDKN1A (rs1321311) and RHPN2 (rs10411210) genes can be used as prognostic biomarkers for patients with surgically resected colorectal cancer. 25799222

2015

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation BEFREE We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755

2012

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation GWASDB We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755

2012

dbSNP: rs1321311
rs1321311
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.830 GeneticVariation GWASCAT We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755

2012