|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Relationship between rs854560 <i>PON1</i> Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease.
|
29118461 |
2017 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender.
|
26467378 |
2016 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality of patients with stable coronary artery disease.
|
25155309 |
2016 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.
|
19226538 |
2009 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In parallel nested case-control studies, the prospective associations between PON1 polymorphisms Q192R and L55M and incident CHD were examined among participants in the Nurses' Health and Health Professionals Follow-up Studies.
|
19443958 |
2009 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In contrast to previous suggestions, this meta-analysis shows no significant association of CHD with the L55M or T(-107)C polymorphism in PON1 or with the S311C polymorphism in PON2.
|
15001326 |
2004 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Two coding polymorphisms, 55M/L and 192Q/R, and a promoter variant, -107C/T, has been extensively studied with respect to susceptibility to CHD.
|
15241482 |
2004 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
PON1 M/L55 mutation protects high-risk patients against coronary artery disease.
|
14996478 |
2004 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genotype frequencies did not differ between cases and controls but the CHD risk associated with smoking was significantly modified by PON1 L55M genotype.
|
14636952 |
2003 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The L55M-glucose interaction differentiated offspring of high CHD risk families, suggesting that it may be of particular relevance for vascular disease and possibly other diabetic complications.
|
11889198 |
2002 |
|
rs854560
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The objective of this study was to determine the possible relationship between the two human PON1 amino acid variants, the Leu55Met and the Gln192Arg polymorphism, and the risk of CHD in a community-dwelling cohort of European ancestry.
|
12417809 |
2002 |