Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs854560
rs854560
CUI: C0025945
Disease: Microangiopathy, Diabetic
Microangiopathy, Diabetic
0.020 GeneticVariation BEFREE 25 Case-control studies were included in the meta-analyses: six on the association between paraoxonase 1 L55M genetic polymorphism and diabetic macroangiopathy risk, nine on the association between L55M and diabetic microangiopathy risk, 12 on the association between Q192R and diabetic macroangiopathy risk, and 12 on the association between Q192R and diabetic microangiopathy risk. 29987647

2018

dbSNP: rs854560
rs854560
CUI: C0025945
Disease: Microangiopathy, Diabetic
Microangiopathy, Diabetic
0.020 GeneticVariation BEFREE In conclusion, all specific enzyme activities of PON1 were lower in patients with type 2 diabetes independent of the -108C/T, 55L/M, or 192Q/R polymorphism, and this impaired PON1 function may be involved in development of diabetic microangiopathy. 11092501

2000