rs1800450
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
However, the other genetic models of rs1800450 (A>B), rs7096206 (Y>X), and rs11003125 (H>L) MBL2 gene polymorphisms did not divulge any association with PTB susceptibility.
|
30666135 |
2019 |
rs1800450
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
The overall results indicated that the MBL-2 rs1800450 (54 A/B) and rs5030737 (52 A/D) polymorphisms were risk factors for PTB, but the MBL-2 rs1800451 (57 A/C) and rs7095891 (+4 P/Q) polymorphisms as protective factors against PTB.
|
30999018 |
2019 |
rs1800450
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
X/Y (rs7096206) and A/B (rs1800450) were genotyped in 765 new patients with active pulmonary TB without HIV infection and 556 controls in Hanoi, Viet Nam.
|
24952212 |
2014 |
rs1800451
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
The current meta-analysis concludes that rs1800451 (A>C) and rs5030737 (A>D) polymorphisms of MBL2 gene play a significant role in PTB susceptibility.
|
30666135 |
2019 |
rs1800451
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
The overall results indicated that the MBL-2 rs1800450 (54 A/B) and rs5030737 (52 A/D) polymorphisms were risk factors for PTB, but the MBL-2 rs1800451 (57 A/C) and rs7095891 (+4 P/Q) polymorphisms as protective factors against PTB.
|
30999018 |
2019 |
rs1800451
|
|
Tuberculosis, Pulmonary
|
|
0.030 |
GeneticVariation
|
BEFREE |
Assuming a recessive mode of inheritance, we found a protective association between TB and the MBL2 G57E variant (odds ratio 0.60, confidence interval 0.4-0.9, P 0.008) and the corresponding LYQC haplotype (P(corrected) 0.007) which applied, however, only to TB caused by M. africanum but not to TB caused by M. tuberculosis.
|
21695215 |
2011 |
rs11003125
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, the other genetic models of rs1800450 (A>B), rs7096206 (Y>X), and rs11003125 (H>L) MBL2 gene polymorphisms did not divulge any association with PTB susceptibility.
|
30666135 |
2019 |
rs11003125
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
In contrast, neither PTB nor STB were found to be associated with rs10065172 and rs11003125.
|
28867622 |
2017 |
rs5030737
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
The current meta-analysis concludes that rs1800451 (A>C) and rs5030737 (A>D) polymorphisms of MBL2 gene play a significant role in PTB susceptibility.
|
30666135 |
2019 |
rs5030737
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
The overall results indicated that the MBL-2 rs1800450 (54 A/B) and rs5030737 (52 A/D) polymorphisms were risk factors for PTB, but the MBL-2 rs1800451 (57 A/C) and rs7095891 (+4 P/Q) polymorphisms as protective factors against PTB.
|
30999018 |
2019 |
rs7095891
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
Conflictingly, a number of MBL2 variants, rs1800450 (A>B), rs1800451 (A>C), rs5030737 (A>D), rs7096206 (Y>X), rs11003125 (H>L), and rs7095891 (P>Q) allele, have been found to be associated with compromised serum levels and pulmonary tuberculosis (PTB) susceptibility.
|
30666135 |
2019 |
rs7095891
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
The overall results indicated that the MBL-2 rs1800450 (54 A/B) and rs5030737 (52 A/D) polymorphisms were risk factors for PTB, but the MBL-2 rs1800451 (57 A/C) and rs7095891 (+4 P/Q) polymorphisms as protective factors against PTB.
|
30999018 |
2019 |
rs7096206
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, the other genetic models of rs1800450 (A>B), rs7096206 (Y>X), and rs11003125 (H>L) MBL2 gene polymorphisms did not divulge any association with PTB susceptibility.
|
30666135 |
2019 |
rs7096206
|
|
Tuberculosis, Pulmonary
|
|
0.020 |
GeneticVariation
|
BEFREE |
X/Y (rs7096206) and A/B (rs1800450) were genotyped in 765 new patients with active pulmonary TB without HIV infection and 556 controls in Hanoi, Viet Nam.
|
24952212 |
2014 |