Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation BEFREE As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6). 29110844

2017

dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation BEFREE This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations. 23959479

2014

dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012

dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation BEFREE However, rs7452888 (6q27) was identified as a possible candidate SNP to influence lung c</span>ancer survival, while stratified analysis hinted at a possible role for rs8034191, rs16969968 (15q25.1) and rs4324798 (6p22.1) in influencing survival time in lun</span>g cancer patients who were never-smokers, based on a small sample. 21750227

2011

dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation BEFREE Genotype data for single-nucleotide polymorphisms at chromosomes 15q25 (rs16969968, rs8034191), 5p15 (rs2736100, rs402710), and 6p21 (rs2256543, rs4324798) from 21 case-control studies for 11 645 lung cancer case patients and 14 954 control subjects, of whom 85% were white and 15% were Asian, were pooled. 20548021

2010

dbSNP: rs4324798
rs4324798
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.740 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009