rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
For rs1859962 at 17q24, genotype dependent expression was observed for the candidate target gene SOX9 in TMPRSS2:ERG fusion-positive PrCa, which was not evident in TMPRSS2:ERG negative tumors.
|
27798103 |
2016 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
We observed no association of the SNPs and the risk of developing PCa (OR 0.84, 95 % CI 0.30-2.38, p = 1.0 to rs1859962 and OR 1.94, 95 % CI 0.57-6.52, p = 0.28 to rs4430796), both sporadic and hereditary.
|
24627192 |
2014 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
Genotype TG on 11q13 (rs7931342, T) could be related to an increased Gleason score, AG on HNF1B (rs4430796, A) could be associated with PSA increase, and TG on 17q24 (rs1859962, G) could be negatively associated with an increased BMI in Chinese men with PCa.
|
23464444 |
2012 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
This identifies a PCa-specific enhancer within the rs1859962 risk LD block that establishes a 1-Mb chromatin loop with the SOX9 gene.
|
22665440 |
2012 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
Our results show that polymorphism of the G allele of SNP rs1859962 is associated with the risk of prostate cancer in a Chinese population.
|
21959049 |
2011 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
Furthermore, the SNPs rs6983561 and rs4430796 were associated with a susceptibility to aggressive prostate cancer, whereas rs1859962 was associated with non-aggressive prostate cancer.
|
21557267 |
2011 |
rs1859962
|
|
Malignant neoplasm of prostate
|
G |
0.770 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies new prostate cancer susceptibility loci.
|
21743057 |
2011 |
rs1859962
|
|
Malignant neoplasm of prostate
|
T |
0.770 |
GeneticVariation
|
GWASDB |
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.
|
19767753 |
2009 |
rs1859962
|
|
Malignant neoplasm of prostate
|
|
0.770 |
GeneticVariation
|
BEFREE |
Recent studies have identified 2 distinct genetic variants along chromosome 17, including allele T of single nucleotide polymorphism rs4430796 on 17q12 and allele G of single nucleotide polymorphism rs1859962 on 17q24, that have been linked to prostate cancer risk.
|
19371897 |
2009 |
rs1859962
|
|
Malignant neoplasm of prostate
|
G |
0.770 |
GeneticVariation
|
GWASDB |
Multiple newly identified loci associated with prostate cancer susceptibility.
|
18264097 |
2008 |